Harnessing apoptosis, a natural cell death process to eliminate damaged cells, has long been a key strategy in cancer research. Recently, Dale Mierke and his collaborators have identified a small molecule that binds to caspase 8 and enhances its activation in response to TRAIL, a central step in apoptosis. Their findings written in, “A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death,” were published recently in Scientific Reports
Investigators Discover Caspase 8 selective Small Molecule to Stimulate TRAIL-induced Apoptosis in Cancer Cells
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