News & Events

  • The Micalizio Group has three new Publications:

    W. S. Kim, K. Du, R. P. Hughes, G. C. Micalizio “Synthetic nat- or ent-steroids in as few as five chemical steps from epichlorohydrin” Nat. Chem. 2017, 9, DOI: 10.1038/nchem.2865.

    M. J. Kier, R. M. Leon, N. F. O’Rourke, G. C. Micalizio “Synthesis of Highly Oxygenated...

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  • The Department of Chemistry seeks an individual who has developed a nationally recognized research program in computational/simulation physical chemistry, and who will excel at teaching in our undergraduate and Ph.D. curricula.

    Applicants must have a Ph.D. in Chemistry or a closely related discipline. The ideal candidate will use a range of computational and simulation methods to advance our understanding of materials, biological or molecular systems, with a possible focus including (...

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  • Vibrio cholerae is responsible for the diarrheal disease cholera that infects millions of people worldwide.  While vaccines protecting against cholera exist, and oral rehydration therapy is an effective treatment method, the disease will remain a global health threat until long-term solutions such as improved sanitation and access to clean water become widely available. Because of this, there is a pressing need for potent therapeutics that can either mitigate cholera symptoms, or act...

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  • The Department of Chemistry is delighted to announce the inaugural First-Year Graduate Student Award (in the amount of $2,500) in honor of two distinguished faculty members: Profs. David M. Lemal and Russell P. Hughes. This award is made possible by the kind support of Dartmouth Chemistry alumni Patrick Lindner, PhD ‘97 and Danielle Lindner, PhD ‘97. This year’s awardees are Nicholas Blelloch and Kelsie Leary. Congratulations.

  • The Radcliffe Institute for Advanced Study at Harvard University has selected Jane E.G. Lipson to be a Radcliffe Institute Fellow  for the 2017-2018 academic year. Lipson joins more than 50 women and men from across the United States and around the world in the 2017–2018 Radcliffe fellowship class who are doing this and more as they pursue work across the arts, humanities, sciences, and social sciences at Harvard’s institute for advanced study.   “It is always wonderful to announce our...

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  • Cover art taken from an invited Perspective in Macromolecules. Published by the American Chemical Society this is the top-cited journal in the field of polymer science.

    Click here to read the paper: http://pubsdc3.acs.org/doi/full/10.1021/acs.macromol.6b00215

  • The Aprahamian group in collaboration with the Liptak group @UVM uncovered
    a new mechanism (SOKR) that explains why aggregation induced emission
    luminogens and florescent molecular rotors emit light (Nature Chemistry, 2016)

    Click here to read the paper: http://www.nature.com/nchem/journal/vaop/ncurrent/full/nchem.2612.html

     

  • “The Micalizio group has established the first convergent coupling reaction capable of establishing trans-fused and angularly substituted decalins in a single step.  Such fused ring systems are ubiquitous in natural and synthetic molecules of therapeutic relevance."

    To read the article click here: https://onlinelibrary.wiley.com/doi/full/10.1002/anie.201606962

  • Direct Self-Assembly of Conductive Nanorods of Metal–Organic Frameworks into Chemiresistive Devices on Shrinkable Polymer Films

    Smith, M. K.; Jensen, K. E.; Pivak, P. A.; Mirica, K. A.*, Chem. Mater., 2016, 28, 5264–5268.

    The Mirica Laboratory has developed an exceedingly simple and rapid approach for integrating conductive nanorods of metal organic frameworks (MOFs) into chemiresistive devices on polymeric substrates. This approach involves fabricating thermally miniaturized...

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  • The Micalizio laboratory has established a synthesis pathway to the pentacyclic core of the rare anticancer and antiviral cortistatins by application of their metallacycle-mediated alkoxide-directed annulative cross-coupling reaction. heir route begins with epichlorohydin, establishes the key trans-fused hydrindane in just six steps, with 9 subsequent steps being employed to establish the ABC-tricyclic system.

    To read the article, please click...

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