Gordon Gribble

Gordon W. Gribble is a native of San Francisco, California, and received his undergraduate education initially at San Francisco City College (AA in 1961) and subsequently at the University of California at Berkeley (BS in 1963), with a major in chemistry and a minor in biochemistry.  He earned a Ph.D. in organic chemistry at the University of Oregon in 1967, where he was a National Institutes of Health Predoctoral Fellow from 1965-67.  He then spent a year doing research as a National Cancer Institute Postdoctoral Fellow at The University of California, Los Angeles.  He joined the faculty of Dartmouth College in 1968 and was promoted to Full Professor of Chemistry in 1980.  He served as Chair from 1988-1991.  In 2005, he was named to the inaugural endowed Chair as “The Dartmouth Professor of Chemistry.”  Professional awards include a National Institutes of Health Research Career Development Award, 1971-1976, a National Science Foundation Science Faculty Professional Development Award, 1977-1978, Dartmouth Senior Faculty Fellowships in 1984, 1991, and 1999.  He was one of six national awardees in 1988 of the American Cyanamid Academic Award.  In 1997 he was awarded the Distinguished Teaching Award by the Dartmouth College senior class, and in 2006 he was presented the Arts and Sciences Graduate Faculty Mentoring Award.  He has been a visiting professor at the California Institute of Technology, the University of Waterloo, the General Electric Company, the University of Hawaii, the University of California at Santa Cruz, and Gettysburg College in Pennsylvania, which included three senior faculty fellowships.   

With the outstanding effort of 46 graduate students, 33 postdoctoral researchers, and 152 undergraduates, Dr. Gribble has published nearly 400 papers and review articles, and four books in the field of organic and environmental chemistry, dealing with the synthesis of biologically active natural products, from plant, insect, and marine sources, new synthetic methodology, heterocyclic organic chemistry, novel DNA bis-Intercalators, and synthetic triterpenoids with unprecedentedly anti-inflammatory activity, one of which, “CDDO” (bardoxolone methyl), completed Phase 3 clinical trials for the treatment of chronic kidney disease in Stage 4 diabetes patients.   Since 1995 he has co-edited the annual series “Progress in Heterocyclic Chemistry”, and has co-authored two editions of “Palladium in Heterocyclic Chemistry”, with Jack Li.  He is a member of the American Chemical Society and the International Society of Heterocyclic Chemistry.

Dr. Gribble has had a long-standing interest in organic chemical toxicity, chemical carcinogenesis, and chemicals in the environment, with particular expertise on pesticides, herbicides, dioxin, chemical warfare, and naturally occurring organohalogen compounds.  He has written, lectured, and consulted extensively on these subjects over the past 35 years, and has written two monographs documenting more than 5,000 naturally occurring organohalogen compounds.

Dr. Gribble’s outside interests include winemaking, tournament chess, and scuba diving.  As a top-ten nationally ranked home winemaker for the past 40 years, he has had an inveterate interest in the chemistry of wine and winemaking.  He won the NH Amateur Chess Championship in 1987.  He has a familial interest in the Battle of Gettysburg and in the WWII battle of Iwo Jima, with personal connections to both signature events in our history.