Selected Publications


Ivan Aprahamian

X. Su, I. Aprahamian*, Hydrazone-Based Switches, Metallo-Assemblies and Sensors, Chem. Soc. Rev. 2014, 43, 1963–1981

Invited contribution to the special issue on “Supramolecular and Dynamic Covalent Reactivity”. Highlighted as an inside front cover.

X. Su, S. Voskian, R. P. Hughes, I. Aprahamian*, Manipulating liquid crystal properties using a pH activated hydrazone switch, Angew. Chem. Int. Ed. 2013, 52, 10734–10739.

Highlighted in Chemistry & Engineering News (September 2, 2013, p43), Medical News Today, Wiley-VCH Hot Topics, Chemistry Views, Liquid Crystals Today, and as a frontispiece.

Y. Yang, R. P. Hughes, I. Aprahamian*, Visible Light Switching of a BF2-Coordinated Azo Compound, J. Am. Chem. Soc. 2012, 134, 15221–15224.

Highlighted in Chemistry & Engineering News (September 17, 2012, p26).

D. Ray, J. T. Foy, R. P. Hughes, I. Aprahamian*, A switching cascade of hydrazone-based rotary switches through coordination-coupled proton relays, Nature Chem. 2012 , 4, 757-762.

Highlighted in the News and Views section of Nature Chemistry.

Y. Yang, X. Su, C. Carroll, I. Aprahamian*, Aggregation Induced Emission in BF2-Hydrazone (BODIHY) Complexes, Chem. Sci. 2012, 3, 610-613.

This paper was one of the top 10 most accessed papers in November 2011, and was highlighted by ACS Noteworthy Chemistry (January 23, 2012)

S. M. Landge, K. Tkatchouk, D. Benitez, D. A. Lanfranchi. M. Elhabiri, W. A. Goddard III, I. Aprahamian*, Isomerization Mechanism in Hydrazone-Based Rotary Switches: Lateral Shift, Rotation, or Tautomerization? J. Am. Chem. Soc. 2011, 133, 9812–9823.

X. Su, T. F. Robbins, I. Aprahamian*, Switching through Coordination-Coupled Proton Transfer, Angew. Chem. Int. Ed. 2011 , 50, 1841–1844.

S. M. Landge, I. Aprahamian*, pH Activated Configurational Rotary Switch: Controlling the E /Z Isomerization in Hydrazones, J. Am. Chem. Soc. 2009, 131, 18269–18271.

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Joseph J. BelBruno

E.A. Karhu, C.R. Ildstad, S. Poggio, V. Furtula, N. Tolstik, I.T. Sorokina, J.J. BelBruno, and U.J. Gibson, “Vapor deposited Cr-doped ZnS thin films: towards optically pumped mid-infrared waveguide lasers” Optics Materials Express, 6, 2947-2955 (2016).

A. Burnin, S. Poggio, J. King and J.J. BelBruno, “Direct growth by arc discharge and computational study of zinc sulfide nanotubes” Journal of Materials Science, 51, 9716-9722 (2016).

“Properties of transition metal substituted zinc sulfide hexamers and dodecamers”, Stefano Poggio,   Brendan Wang,  Ursula J. Gibson and   Joseph J. BelBruno, Phys. Chem. Chem. Phys., (2015) 17, 14208-14214

“Thermochemical study of amino acid imprinted polymer films” Ziyi Chai and Joseph J. BelBruno, Journal of Molecular Recognition (2015) 28 651-655.

"Evidence of chromium-cobalt binary cluster formation by pulsed laser evaporation", Andrei Burnin, Joseph J. BelBruno and Ursula Gibson, International Journal of Mass Spectrometry (2015) 380 7-11.

“Band-edge modification and mid-infrared absorption of co-deposited FexZn1-xS thin films”, Nelly-Ann Molland, Zahra Ghadyani, Eric A. Karhu, Stefano Poggio, Mohammadreza Nematollahi, Morten Kildemo, Turid W. Reenaas, Joseph J. BelBruno, and Ursula J. Gibson, Optical Materials Express (2015) 7 1613-1620.

S. Antwi-Boampong, J.S. Peng, J. Carlan and J.J. BelBruno, “A molecularly imprinted fluoral-p/polyaniline double layer sensor system for selective sensing of formaldehyde”, Sensors Journal, IEEE 14, 1490-1498 (2014).

Sadik Antwi-Boampong, Kristina Mani, Jean Carlan and Joseph J. BelBruno, "A selective molecularly imprinted polymer-carbon nanotube sensor for cotinine sensing."Journal of Molecular Recognition 27, 57-63 (2014).

Yuan Liu, Sadik Antwi-Boampong, Joseph J. BelBruno, Mardi A. Crane, and Susanne E. Tanski. "Detection of secondhand cigarette smoke via nicotine using conductive polymer films."Nicotine & Tobacco Research (2013). doi: 10.1093/ntr/ntt007

Jinpeng Lv, Chundong Li, and J. J. BelBruno. "Defect evolution on the optical properties of H+-implanted ZnO whiskers."CrystEngComm 15, 5620-5625 (2013).

Jinpeng Lv, Chundong Li, and J. J. BelBruno. "Characteristics of point defects on the optical properties of ZnO: revealed by Al–H co-doping and post-annealing."RSC Adv. 3, 8652-8656 (2013).

Sadik Antwi‐Boampong, Yuan Liu, Asta Richter, and Joseph J. BelBruno. "Effect of the host polymer on the nanomechanical and morphological properties of templated polymer films."Journal of Applied Polymer Science 130, 877-883 (2013).

April D. Lewoczko, Joseph J. BelBruno, and Stefan T. Bromley. "Effect of spin ordering on structure and structural transitions in the (MnS)6 magic cluster."Chemical Physics Letters 556, 207-210 (2013).

Sadik Antwi-Boampong and Joseph J. BelBruno. "Detection of formaldehyde vapor using conductive polymer films."Sensors and Actuators B 182, 300-306 (2013).

April D. Lewoczko and Joseph J. BelBruno. "Impact of surface steps and oxygen pre-coverage on the adsorption of methylamine on gold."Phys. Chem. Chem. Phys. 15, 4707-4714 (2013).

Gian Giacomo Asara, April D. Lewoczko, Andrei Burnin, Joseph J. BelBruno, and Stefan T. Bromley. "Interplay between Magnetism and Magicness in Nanoclusters."The Journal of Physical Chemistry C 116, 20625-20632 (2012).

Asta Richter and Joseph J. BelBruno. "Characterization of functional states in nicotine and cotinine imprinted poly (vinylphenol) films by nanoindentation."Journal of Applied Polymer Science 124, 2798-2806 (2012).

S.W.R. Dunbar and J.J. BelBruno, "Molecularly imprinted polymer-carbon nanotube sensor targeted to cotinine",Chemical Sensors, 2, 14 (2012).

A. Daigle and J.J. BelBruno, "Density Functional Theory Study of the Adsorption of Nitrogen and Sulfur Atoms on Gold (111), (100), and (211) Surfaces",J. Physical Chemistry C 115, 22987-22997 (2011).

A. Daigle and J.J. BelBruno, "Density functional theory study of the adsorption of oxygen atoms on gold (111), (100) and (211) surfaces",Surface Science 605, 1313 (2011).

J.J. BelBruno, G. Zhang and U.J. Gibson, "Capacitive sensing of amino acids in molecularly imprinted nylon films",Sensors and Actuators B 155, 915 (2011).

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Charles L. Braun

C. Zhong, J. Zhou and C. L. Braun, Electron-transfer Absorption of Sterically Bulky Donor-acceptor Pairs: Electron Donor-acceptor Complexes or Random Pairs? J. Photochem. Photobiol. A. Chem., 2003, in press.

J. Zhou, C. Zhong, T. M. Francis, and C. L. Braun, Radiative Exciplexes of 1,2,4,5-Tetracyanobenzene with Sterically Hindered Alkylbenzenes, J. Phys. Chem.,2003, 107A, in press.

S. N. Smirnov, P. A. Liddell, I. V. Vlassiouk, A. Teslja, D. Kuciauskas, C. L. Braun, A. L. Moore, T. A. Moore, and D. Gust, Characterization of the Giant Transient Dipole Generated by Photoinduced Electron Transfer in a Carotene-Porphyrin-Fullerene Molecular Triad, J. Phys. Chem. 2003, 107A, 7567- 7573

J. Zhou, B. R. Findley, T. M. Francis, E. A. Nytko, C. L. Braun, The Solution Dynamics of Photoinduced Geminate Radical Ion Pairs: Free Ion Formation,Chem. Phys. Letters, 2002, 362, 63-71.

J. Zhou, R.P. Shah, B.R. Findley, C.L. Braun, Long Distance Photoinduced Electron Transfer in Solutions: A Mechanism for Producing Large Yields of Free Ions by Electron Transfer Quenching, J. Phys. Chem., 2002, 106A, 12-20.

J. Zhou, B.R. Findley, C.L. Braun, N. Sutin, The Separation Distance Distribution in Electron-Donor-Acceptor Systems and the Wavelength Dependence of Free Ion Yields, J. Chem. Phys., 2001, 114, 10448-10456.

J. Zhou, B.R. Findley, A. Teslja, C.L. Braun, N. Sutin, Ion Pairs from Photoexcited, "Random" Electron Dopnors and Acceptors: Alkylbenzenes and Tetracyanoethylene, J. Phys. Chem., 2000, 104, 11512-11521.

S.N. Smirnov, C.L. Braun, Photoinduced Free Carrier Yields in High Fields: Field Dependent Distribution Functions. Journal of Imaging Science and Technology, l999, 43, 425-429.

S.N.Smirnov, C.L.Braun, Advances in the Transient DC Photocurrent Technique for Excited State Dipole Moment Measurements. Rev. Sci. Instr., 1998, 69, 2875.

S.E.Mylon, S.N.Smirnov, C.L.Braun, Exciplex Dipole Moments: Cyanoanthracenes Acceptors and Methyl-Substituted Benzene Donors. J. Phys. Chem., 1998, 102, 6558.

B.R.Findley, S.N.Smirnov, C.L.Braun, Larger Than Expected Free Ion Yields from the Photoexcited Trans-Stilbene/Fumaronitrile CT Complex in a Variety of Solvents. J. Phys. Chem., 1998,102, 6385.

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Robert S. Cantor

R.S. Cantor, Front. Synaptic Neurosci. (2015) 7:15. "The evolutionary origin of the need for sleep: an inevitable consequence of synaptic neurotransmission?" doi: 10.3389/fnsyn.2015.00015

D.K. Lee, D.J. Albershardt and R.S. Cantor, Biophys. J. (2015) 108, 1081-1093. "Exploring the mechanism of general anesthesia: Kinetic analysis of GABAA receptor electrophysiology."

J.A. Sonner, R.S. Cantor, Annu. Rev. Biophysics (2013) 42, 143-67. "Molecular mechanisms of drug action: An emerging view".

R.S. Cantor, P.S. Milutinovic and R. Haseneder, Soft Matter (2009) 5, 3266-3278. "A kinetic model of ion channel electrophysiology: bilayer-mediated effects of agonists and anesthetics on protein conformational transitions". Invited contribution to a special theme issue on Membrane Biophysics.

P.M. Milutinovic, L. Yang, R.S. Cantor, E.I. Eger II and J.M. Sonner, Anesthesia and Analgesia (2007) 105, 386-392. "Anesthetic-like modulation of γ-aminobutyric acid type A, strychnine-sensitive glycine, and N-methyl-D-aspartate receptors by coreleased neurotransmitters".

J.T. Mohr, G.W. Gribble, S.S. Lin, R.G. Eckenhoff and R.S. Cantor, J. Med. Chem. (2005) 48, 4172-4176. "Anesthetic potency of two novel synthetic polyhydric alkanols longer than the n-alkanol cutoff: Evidence for a bilayer-mediated mechanism of anesthesia?".

R.S. Cantor, Biochemistry (2003) 42, 11891-11897. "Receptor desensitization by neurotransmitters in membranes: are neurotransmitters the endogenous anesthetics?".

R.S. Cantor, Biophys. J. (2002) 82, 2520-2525. "Size distribution of barrel-stave aggregates of membrane peptides: Influence of the bilayer lateral pressure profile".

R.S. Cantor, J. Phys. Chem. B (2001) 105, 7550-7553. "Bilayer partition coefficients of alkanols: predicted effects of varying lipid composition".

R. S. Cantor, Biophys. J. (2001) 80, 2284-2297. "Breaking the Meyer-Overton rule: predicted effects of varying stiffness and interfacial activity on the intrinsic potency of anesthetics".

R. S. Cantor, Prog. Anesth. Mech. (2000) 6, 80-85. "The correlation of anesthetic potency with stiffness and interfacial activity".

R. S. Cantor, Biophys. J. (1999) 77, 2643-2647. "Solute modulation of conformational equilibria in intrinsic membrane proteins: apparent 'cooperativity' without binding".

R. S. Cantor, Chem. Phys. Lipids (1999) 101, 45-56. "The influence of membrane lateral pressures on simple geometric models of protein conformational equilibria".

R. S. Cantor, Biophys. J. (1999) 76, 2625-2639. "Lipid composition and the lateral pressure profile in bilayers."

R. S. Cantor, Biochemistry (1997) 36, 2339-2344. "The lateral pressure profile in membranes: a physical mechanism of general anesthesia."

R. S. Cantor, J. Phys. Chem. (1997) 101, 1723-1725. "Lateral pressures in cell membranes: a mechanism for modulation of protein function."



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Robert Ditchfield

Lancaster, C. R. D., Hunte, C., Kelley, J., Trumpower, B. L., and Ditchfield, R. "A Comparison of Stigmatellin Conformations, Free and Bound to the Photosynthetic Reaction Center and the Cytochrome bc1 Complex." J. Mol. Biol. 368, 197 (2007).

Circumannular long range orbital interactions affect thefree energy of activation for the inversion of groups on nitrogen in3-imino-2,2,4,4-tetramethylcyclobutanones, James J. Worman, Robert Ditchfield,Allen Chong, Grzegorz Mloston, and Martha Wozicka, J. Amer. Chem. Soc., Book of Abstracts, 229thACS National Meeting, San Diego, CA (2005), ORGN-474.

Hydroxycarbocation - π interaction: A computational andexperimental study of protonation of aromatic ketones, Bobbijo van Beusichem,Celeste P. Viscardi, Thomas A. Spencer, Jr., and Robert Ditchfield, Abstr. Pap. J. Amer. Chem. Soc., (2000), ORGN-497.

Benzobicyclo[4.2.1]nonene model system for study ofcarbocation-π interaction, Janeta V. Popovici-Muller, Robert Ditchfield, andThomas A. Spencer, Jr., J. Amer. Chem. Soc., Book of Abstracts, 219th ACS National Meeting, SanFrancisco, CA (2000), ORGN-508.J. Am. Chem. Soc.

Carbocation-π Interaction: Computational Study ofComplexation of Methyl Cation with Benzene and Comparisons with RelatedSystems, P. C. Miklis, R. Ditchfield, and T. A. Spencer. J. Am. Chem. Soc., 120,10482, (1998)

Metal Complexes of Mesitylphosphine: Synthesis, Structure,and Spectroscopy I. V. Kourkine, S. V. Maslennikov, R. Ditchfield, D. S.Glueck, G. P. A. Yap, L. M. Liable-Sands, A. L. Rheingold, InorganicChemistry, 35, 6708 (1996).

Synthesis and Dynamic NMR Studies of h3- Triphenyl - and h3-Trimethylcyclopropenyl Complexes of Ruthenium, [Ru(h5 - C5R5)(h3 - C3R'3)X2] (R= H, Me; R' = Me, Ph; X = Cl, Br, I). Extended Hückel Molecular Orbital Study of Barriers to Rotation of h3 -Cyclopropenyl Ligands in Isoelectronic Ruthenium and Molybdenum Complexes, R.Ditchfield, R. P. Hughes, D. S. Tucker, E. P. Bierwagen, J. Robbins, D. J.Robinson, and J. A. Zakutansky, Organometallics, 12, 2258 (1994)

Ab-Initio Computations of 29SiNuclear Magnetic Resonance Chemical Shifts for a range of representativecompounds, J.R. van Wazer, C.S. Ewig, and R. Ditchfield, J. Phys. Chem., 95,2222 (1990).

Phosphorus Compounds and their 31P Chemical Shifts, J.R. van Wazer and R. Ditchfield, Chapter 1,p.1 in Phosphorus NMR in Biology, (edited by C.T. Burt), (CRC Press,1987).

Proton and Carbon-13 Chemical Shifts: Comparison between Theory andExperiment, C. Rohlfing, L.C. Allen, and R. Ditchfield, Chemical Physics, 87, 9(1985).

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David S. Glueck

David S. Glueck

Reynolds, S. C.; Hughes, R. P.; Glueck, D. S.; Rheingold, A. L. Org. Lett. 2012, 14, 4238–4241. Synthesis, Reactivity, and Resolution of a C2–Symmetric, P–Stereogenic Benzodiphosphetane, a Building Block for Chiral Bis(phosphines).

Guino-o, M. A.; Zureick, A. H.; Blank, N. F.; Anderson, B. J.; Chapp, T. W.; Kim, Y.; Glueck, D. S.; Rheingold, A. L. Organometallics 2012, 31, 6900-6910. Synthesis and Structure of Platinum Bis(phospholane) Complexes Pt(diphos*)(R)(X), Catalyst Precursors for Asymmetric Phosphine Alkylation.

Chapp, T. W.; Schoenfeld, A. J.; Sanderson, M. D.; Chang, C. L.; Glueck, D. S.; Golen, J. A.; Moore, C. E.; Rheingold, A. L. Organometallics 2012, 31, 5573–5585. Synthesis, Structure, Dynamics, and Selective Methylation of Platinum and Palladium Diphosphametallacyclobutane Complexes.

Cain, M. F.; Glueck, D. S.; Golen, J. A.; Rheingold, A. L. Organometallics 2012, 31, 775-778. Asymmetric Synthesis and Metal Complexes of a C3-Symmetric P-Stereogenic Triphosphine, (R)-MeSi(CH2PMe(t-Bu))3 (MT-Siliphos).

Zuzek, A. A.; Reynolds, S. C.; Glueck, D. S.; Golen, J. A.; Rheingold, A. L. Organometallics 2011, 30, 1812-1817. Synthesis and Structure of Gold and Platinum Menthyl Complexes.

Seibert, A. R.; Cain, M. F.; Glueck, D. S.; Nataro, C. J. Organomet. Chem.2011, 696, 2259-2262. Electrochemistry of P(CH2Fc)3 and derivatives.

Glueck, D. S. Catal. Sci. Technol. 2011, 1, 1099-1108. Selectivity via catalyst or substrate control in catalytic asymmetric transformations of bifunctional symmetrical substrates. (invited review)

Cain, M. F.; Reynolds, S. C.; Anderson, B. J.; Glueck, D. S.; Golen, J. A.; Moore, C. E.; Rheingold, A. L. Inorg. Chim. Acta 2011, 369, 55-61. Synthesis, Structure and Spectroscopic Properties of 2,3-bis(diphenylphosphino)quinoxaline (dppQx) and Its Copper(I) Complexes. (special R.G. Bergman issue)

Cain, M. F.; Hughes, R. P.; Glueck, D. S.; Golen, J. A.; Moore, C. E.; Rheingold, A. L. Inorg. Chem.2010, 49, 7650–7662. Synthesis and Structure of Intermediates in Copper-Catalyzed Alkylation of Diphenylphosphine. (cover picture)

Glueck, D. S. Top. Organomet. Chem.2010, 31, 65-100. Recent Advances in Metal-Catalyzed C–P Bond Formation. (invited review)

Lane, E. M.; Chapp, T. W.; Hughes, R. P.; Glueck, D. S.; Feland, B. C.; Bernard, G. M.; Wasylishen, R. E.; Rheingold, A. L. Inorg. Chem.2010, 49, 3950–3957. Synthesis of Gold Phosphido Complexes Derived from Bis(secondary) Phosphines. Structure of Tetrameric [Au(MesP(CH2)3PMes)Au]4.

Chapp, T. W.; Schoenfeld, A. J.; Glueck, D. S. Organometallics2010, 29, 2465-2473. Effects of Linker Length on the Rate and Selectivity of Platinum-Catalyzed Asymmetric Alkylation of the Bis(isitylphosphino)alkanes IsHP(CH2)nPHIs (Is = 2,4,6-(i-Pr)3C6H2, n = 1–5).

Chapp, T. W.; Glueck, D. S.; Golen, J. A.; Moore, C. E.; Rheingold, A. L. Organometallics2010, 29, 378-388. Platinum-Catalyzed Asymmetric Alkylation of Bis(isitylphosphino)ethane: Stereoselectivity Reversal in Successive Formation of Two P-C Bonds.

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Gordon Wayne Gribble

“Total Synthesis of Atorvastatin via a Late-Stage, Regioselective 1,3-Dipolar Münchnone Cycloaddition”; Lopchuk, J.M; Gribble, G.W. Tetrahedron Lett. 2015, 56, 3208-3211 (Invited for the Henry Wasserman Special Issue).

“Synthesis of Heteraryl-Substituted Pyrroles via the 1,3-Dipolar Cycloaddition of Unsymmetrical Münchnones and Nitrovinyl Heterocycles”; Lopchuk, J.M.; Song, M.; Butler, B.; Gribble, G.W. Synthesis, 2015, 47, 2776-2780 (Invited for a Special Issue on Cycloaddition Reactions and Methods).

“A Recent Survey of Naturally Occurring Organohalogen Compounds”; Gribble, G.W. Environ. Chem. 2015, 12, 396-405 (Special Issue on “Natural Halogenation).

 “Novel Synthesis of 1-Bromo-8-methylnaphthalene and 1-Bromo-45-methylnaphthalene”; Onyango, E.O.; Kelley, A.R.; Qian, D.C.; Gribble, G.W. J. Org. Chem. 2015, 80, 5970-5972.

“Biological Activity of Recently Discovered Halogenated Marine Natural Products”; Gribble, G.W. Marine Drugs, 2015, 13, 4044-4136.

“Novel Synthetic Pyridyl Analogues of CDDO-Imidazolide Are Useful New Tools in Cancer Prevention”; Cao, M.; Onyango, E.O.; Williams, C.R.; Royce, D.B.; Gribble, G.W.; Sporn, M.B.; Liby, K.T. Pharmacol. Res., 2015, 100, 135-147.

“Synthesis, Crystal Structures and DFT Calculations of Three New Cyano(phenylsulfonyl)indoles and a Key Synthetic Precursor Compound”; Montgomery, W.L.; Lopchuk, J.M.; Gribble, G.W.; Jasinski, J.P. Crystals, 2015, 5, 376-393.

“Triple Benzannulation of Naphthalene via a 1,3,6-Naphthotriyne Synthetic Equivalent. Synthesis of Dibenz[a,c]anthracene”; Mannes, P.Z.; Onyango, E.O.; Gribble, G.W. J. Org. Chem. 2015, 80, 11189-11192.

“Synthesis of a Monofluoro 3-Alkyl-2-hydroxy-1,4-naphthoquinone: A Potential Anti-Malarial Drug”; Kim, E.E.; Onyango, E.O.; Fu, L.; Gribble, G.W. Tetrahedron Lett. 2015, 56, 6707-6710.

“What Ever Happened to Dioxin? An Update on the “Doomsday Chemical” of the 1970s and 1980s”; Gribble, G.W. Priorities 2016, March, 11-13.

“Three-Component Reductive Alkylation of 2-Hydroxy-1,4-naphthoquinones with Lactols”; Kim, E.E.; Onyango, E.O.; Pace, J.R.; Abbot, T.M.; Fu, L.; Gribble, G.W. Tetrahedron Lett. 2016, 57, 864-867.

“Metal-Catalyzed Coupling with Heterocycles”; Badenock, J.C.; Gribble, G.W. Advances in Heterocyclic Chemistry 2016, 120, 99-136.

“Indole Ring Synthesis – From Natural Products to Drug Discovery”; Gribble, G.W.; John Wiley & Sons, Chichester, UK, 2016.

"Six-Membered Ring Systems:  Pyridine and Benzo Derivatives"; Gribble, G.W.; Kishbaugh, T.L.S. Prog. Heterocycl. Chem. 2016, 28, 391-437.

“Synthesis of a Masked 2,3-Diaminoindole”; Mannes, P.Z.; Onyango, E.O.; Gribble, G.W. J. Org. Chem. 2016, 81, 12478-12481.


"tert-Butyl 2,3-Dihydro-1H-cyclopenta[b]indole-4-carboxylate"; Jordan, J.A.; Badenock, J.C.; Gribble, G.W.; Kaur, M.; Jasinski, J.P. IUCrDATA 2016, 1, 161468.

“What Ever Happened to Dioxin?  An Update on the “Doomsday Chemical” of the 1970s and 1980s”; Gribble, G.W. Priorities 2016, March, 11-13.

"Synthesis, Crystal Structures, and DFT Calculations of Three Novel 1-(Phenylsulfonyl)indoles"; Mannes, P.Z.; Kaur, M.; Onyango, E.O.; Gribble, G.W.; Jasinski, J.P. J. Chem. Crystallogr. 2017, 47, 10-21.

“Photo-degradation of 2,4-Dinitroanisole (DNAN):  An Emerging Munitions Compound”; Taylor, S.; Walsh, M.E.; Becher, J.B.; Ringelberg, D.B.; Mannes, P.Z.; Gribble, G.W. Chemosphere 2017, 167, 193-203.

“A New Class of Inhibitors of the AraC Family of Virulence Regulator Vibrio cholera ToxT”; Kelley, A.R.; Onyango, E.O.; Pellegrini, M.; Kovacikova, G.; Taylor, R.K.; Gribble, G.W.; Kull, J.F. Scientific Reports 2017, 7, 45011.


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Russell Profit Hughes

Russell Profit Hughes

Generation of Hydrofluoronickelacycles from Trifluoroethylene and Ni(0): Ligand Effects on Regio-/Stereo-Selectivity and Reactivity.  Katie A. Giffin, Lorraine A. Pua, Sarah Piorkowski, Bulat Gabidullin, Ilia Korobkov, Russell P. Hughes, and R. Tom Baker.  J. Amer. Chem. Soc., 2017, 139, 4075-4086.

Fluorocarbene, Fluoroolefin, and Fluorocarbyne Compexes of Rh.  Christopher J. Pell, Yanjun Zhu, Rafael Huacuja, David E. Herbert, Russell P. Hughes, and Oleg V. Ozerov.  Chemical Science, 2017, 8, 3178-3186.

Cationic Two-Coordinate Complexes of Pd(I) and Pt(I) Have Longer Metal-Ligand Bonds Than Their Neutral Counterparts.  Morgan C. MacInnis, Jessica C. DeMott, Eva M. Zolnhofer, Jia Zhou, Karsten Meyer, Russell P. Hughes, and Oleg V. Ozerov.  Chem.., 2016, 1, 902-920.

X-ray structures and electronic properties of the 1, 1', 2, 2' - and 1, 1', 3, 3' - tetra-t-butylferrocenium (1+) cations.  Kristina M. Gansle, Alexander E. Gash, C. Kevin Chambliss, Brady J. Clapsaddle, Brian S. Newell, Susie M. Miller, Oren P. Anderson, Russell P. Hughes, and Steven H. Strauss.  Polyhedron, 2016, 121, 88-94.

A Nascent Phosphinidene Trapped in a Fluxional NCN Pincer.  Jakub Hyvel, Wesley Y. Yoshida, Arnold L. Rheingold, Russell P. Hughes, and Matthew F. Cain.  Chemistry - A European Journal, 2016, 22, 17562-17565.

Coordination contributions to protein stability in metal-substituted carbonic anhydrase.  George P. Lisi, Russell P. Hughes, and Dean E. Wilcox.  J. Biol. Inorg. Chem, 2016, 21, 659-667.

Synthesis of a Tris(phosphaalkene)phosphine Ligand and Fundamental Organometallic Reactions on Its Sterically Shielded Metal Complexes.  Preston M. Miura-Akagi, Mika L. Nakashige, Caitlin K. Maile, Shelly M. Oshiro, Joshua R. Gurr, Wesley Y. Yoshida, A. Timothy Royappa, Colleen E. Krause, Arnold L. Rheingold, Russell P. Hughes, and Matthew F. Cain.  Organometallics, 2016, 35, 2224-2231.

Streamlined Preparation and Coordination Chemistry of Hybrid Phosphine-Phosphaalkene Ligands.  Kevin W. Magnuson, Shelly M. Oshiro, Joshua R. Gurr, Wesley Y. Yoshida, Milan Gembicky, Arnold L. Rheingold, Russell P. Hughes, and Matthew F. Cain.  Organometallics, 2016, 35, 855-859.

A New Stepwise Mechanism for Formation of Metallacyclobutane via a Singlet Diradical Intermediate.  Jay T. Fuller, Daniel J. Harrison, Matthew C. Leclerc, R. Tom Baker, Daniel H. Ess, and Russell P. Hughes.  Organometallics, 2015, 34, 5210-5213.

Dearomative Indole (3+2) Reactions with Azaoxyallyl Cations - New Method for the Synthesis of Pyrroloindolines.  Maria C. DiPoto, Russell P. Hughes, and Jimmy Wu.  J. Amer. Chem. Soc., 2015, 137, 14861-14864.

Synthesis, Structure, and Reactivity of Iridium Perfluorrocarbene Complexes: Regio- and Stereo-specific Addition of HCI Across a Metal Carbon Double Bond.  Jian Yuan, Cheryl J. Bourgeois, Arnold L. Rheingold, and Russell P. Hughes.  Dalton Transactions, 2015, 44, 19528-19542.

Bonding Analysis of TM(cAAC)2 (TM=Cu, Ag, Au) and the Importance of reference State.  Clark R. Landis, Russell P. Hughes, and Frank Weinhold.  Organometallics, 2015, 34, 3442-3449.

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image of Peter Jacobi

Peter Alan Jacobi

"Toward the Synthesis of Cobyric Acid. Enantioselective Syntheses of Completely Differentiated Ring D Synthons," Wang, H.; Tassa, C.; Jacobi, P. A. Org. Lett. 2008, 10, 2837.

"The Localization and Photosensitization of Modified Chlorin Photosensitizers in Artificial Membranes," Ben Dror, S.; Bronshtein, I.; Garini, Y.; O'Neal, W.G.; Jacobi, P.A.; Ehrenberg, B. Photochem. Photobiol. Sci. 2009, 8, 354-361.

"The Binding of Analogs of Porphyrins and Chlorins With Elongated Side Chains to Albumin," Ben-Dror, S.; Bronshtein, I.; Weitman, H.; Smith, K. M.; O'Neal, W. G.; Jacobi, Peter A.; Ehrenberg, B.Eur. Biophys. J. 2009, 38, 847-855.

"An Improved Synthesis of a Ring-C Precursor to Cobyric Acid," Wang, H.; Jacobi, P.A. Arkivoc 2010, 15.

"4-Alkynoic Acids in the Synthesis of Biologically Important Tetrapyrroles," Jacobi, P.A.; Brielmann, H.L.; Chiu, M.; Ghosh, I.; Hauck, S.I.; Lanz, S.; Leung, S.; Li, Y.; Liu, H.; Löwer, F.; O'Neal, W.G.; Pippin, D.; Pollina, E.; Pratt, B.A.; Robert, F.; Roberts, W.P.; Tassa, C.; Wang., H. Heterocycles 2011, 82, 1029-1081.

"Furanosteroid Studies. Improved Synthesis of the A,B,C,E-Ring Core of Viridin," Mascall, K.C.; Jacobi, P.A. Tetrahedron Lett. 2012, 53, 1620-1623.

"Synthetic Studies on Furanosteroids: Construction of the Viridin Core Structure via Diels-Alder/retro-Diels-Alder and Vinlogous Mukaiyama Aldol-Type Reaction," Onyango, E.O.; Jacobi, P.A. J. Org. Chem. 2012, 77, 7411-7427.

"Synthesis of an Advanced Precursor Toward Demethoxyviridin," Onyango, E.O.; Jacobi, P.A. Synthetic Communications, 2013, 43, 2748-2755.

"Constructing the Heterocyclic Core of Viridin and Wortmannin," Jacobi, P.A.; Konekamp T.; Mascall, K.C.M.; O'Connor, R.T.; Onyango, E.O.; Sessions, E.H.  Advances in Heterocyclic Chemistry, 2013, 110, 119-144;  Katritzky, A.R., editor; Academic Press (Elsevier Inc); ISBN: 9780124081000.

"Synthetic Studies on Furanosteroids.  Functionalization of Ring A of the Viridin Core Skeleton," Mascall, K.C.; Jacobi, P.A.  Heterocycles, 2014, 88, 1527-1538

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Chenfeng Ke

Y. Lin,# X. Jiang,# (equal contribution) S. T. Kim,  S. B. Alahakoon, X. Hou, Z. Zhang, C. M. Thompson, R. A. Smaldone, and C. Ke,* "An Elastic Hydrogen-bonded Crosslinked Organic Framework for Effective Iodine Capture in Water" 
J. Am. Chem. Soc., 2017139, 7172–7175.  Highlighted by EurekAlert!,  共同ニュース,  X-mol and others

Q. Lin, X. Hou, and C. Ke,* "Ring Shuttling Controls Macroscopic Motion in a Three-Dimensional Printed Polyrotaxane Monolith" Angew. Chem. Int. Ed.2017, 56,  4452 – 4457. DOI: 10.1002/anie.201612440
​​​Highlighted by The Conversation3ders.orgEurekAlert!phys.orginverseobservernwi.comNanowerkHealth Medicine NetworkScienceNewsline, ​X-mol and many more​

C. Ke, "Nanomachines: A light-powdered clockwork" ​​Nature Nanotechnology201712, 504-506. DOI:10.1038/nnano.2017.44.

X. Hou, #C. Ke,# (equal contribution) C. Bruns, P. McGonigal, R. Pettman and J.F. Stoddart, * Nature Communications 2015, 6, 6884 doi: 10.1038/ncomms7884.  Highlighted by The Wall Street Journal, C&E News, Chicago Tribune, Chemistry Views, The Conversation, BBC Focus and many others.

X. Hou, #C. Ke,# (equal contribution) C. Cheng, N. Song, A.K. Blackburn, A.A. Sarjeant, Y. Y. Botros, Y.W. Yang and J.F. Stoddart, * Chem. Commun., 2014, 50, 6196-6199.  Front Cover.  doi: 10.1039/c4cc00733f. 

C. Ke, N.L. Strutt, H. Li, X. Hou, K.J. Hartlieb, P. McGonigal, Z. Ma, J. Lehl, C.L. Stern, C. Cheng, Z. Zhu, N.A. Vermeulen, T.J. Mead, Y.Y. Botros and J.F. Stoddart, * J. Am. Chem. Soc.,  2013, 135, 17019-17030. doi: 10.1021/ja407229h. 

C. Ke, R.A. Smaldone, T. Kikuchi, H. Li., A.P. Davis and J.F. Stoddart, * Angew. Chem. Int. Ed.,  2013, 52, 381-387.   doi: 10.1002/anie.201205087. 

C. Ke, H. Destecroix, M.P. Crump and A.P. Davis, * Nature Chemistry,  2012, 4, 718-723. doi: 10.1038/nchem.1409.

C. Ke, C. Yang, T. Mori, T. Wada, Y. Liu* and Y. Inoue, * Angew. Chem. Int. Ed.,  2009, 48, 6675-6677.   doi: 10.1002/anie.200902911. 

X. Liu, *C. Ke, H.Y. Zhang, J. Cui and F. Ding,  J. Am. Chem. Soc., 2008, 130, 600-605.   doi: 10.1021/ja075981v. 

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F. Jon Kull

F. Jon Kull

Sharyn A. Endow, F. Jon Kull and Honglei Liu. (2010)“Kinesins at a glance”. Journal of Cell Science . Oct 15;123(Pt 20):3420-4. PMID: 20930137

Yu Cheng Zhao, F. Jon Kull, Jared C. Cochran.“Modulation of the kinesin ATPase cycle by neck linker docking and microtubule binding”. Journal of Biological Chemistry . Aug 13;285(33):25213-20. PMCID: PMC2919084.

Elisabeth Heuston, C. Eric Bronner, F. Jon Kull and Sharyn A Endow. (2010)“A kinesin motor in a force-producing conformation”. BMC Structural Biology . Jul 5;10:19. PMCID: PMC2906495.

Lowden, M.J., K. Skorupski, M. Pellegrini, M.G. Chiorazzo, R.K. Taylor, and F.J. Kull. (2010) Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proc. Natl. Acad. Sci. USA . Feb 16;107(7):2860-5. PMCID: PMC284031.

Cochran, J.C., Sindelar, C.V., Mulko, N.K., Collins, K.A., Kong, S.E., Hawley, R.S., and Kull, F.J. (2009) The ATPase Cycle of the Nonmotile Kinesin NOD Allows Microtubule Plus-End Tracking and Drives Chromosome Movement. Cell . Jan 9;136(1):110-22. PMID: 19135893.

Cochran, J.C., and Kull, F.J. (2008) Kinesin Motors: No Strain, No Gain. Cell. Sep 19;134(6):918-9. PMID: 18805085.

De Silva, R.S., Kovacikova, G., Lin, W., Taylor, R.K., Skorupski, K., and Kull, F.J. (2007) Crystal structure of the bacterial virulence gene regulator HapR, J. Bacteriology. Aug;189(15):5683-91.

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Image of David Lemal

David Lemal

Junk, C. P.; He, Y.; Zhang, Y.; Smith, J. R.; Gleiter, R.; Kass, S. R.; Jasinski, J. P.; Lemal, D. M. "Synthesis and Properties of the Strained Alkene Perfluorobicyclo[2.2.0]hex-1(4)-ene,"J. Org. Chem. 2015, 80, 1523-32.

Lemal. D. M.; Akashi. M.; Lou, Y.; Kumar, V. "Tetrafluorothiophene S,S-Dioxide: A Perfluorinated Building Block," J. Org. Chem. 2013, 78, 12330-37.  Selected as a Featured Article.

Ramanathan, S.; Sang, D.; Kumar, V.; Lemal, D. M. "Synthesis of Tetrafluorocatechol" In "Efficient Preparations of Fluorine Compounds;" Roesky, H. W., Ed.; Wiley: Hoboken, NJ, 2013; Chap. 41.

Buzby, J. M.; Barefoot, A. C., III; Grayston, M. W.; Laganis, E. D.; Waldron, R.F.; Lemal, D. M. "Synthesis of Octafluorocyclooctatetraene" In "Efficient Preparations of Fluorine Compounds;" Roesky, H. W., Ed.; Wiley: Hoboken, NJ, 2013; Chap. 49.

Kumar, V.; Ramanathan, S.; Sang, D.; Chen, X.; Lemal, D. M. "The Multifaceted Reactivity of o-Fluoranil," J. Org. Chem. 2012, 77, 966-70.

Kumar, V.; Lemal, D.M. "Photochemistry of o-Fluoranil," J. Org. Chem. 2012, 77, 5017-21.

Lemal, D. M. "Chemistry of Hexafluorobicyclo[1.1.0]butane: A Computational Study," J. Org. Chem. 2010, 75, 6411-5.

Lemal, D. M.; Sang, D.; Ramanathan, S. "o-Fluoranil: Stereochemistry and Mechanism of its Diels-Alder Reactions," J. Org. Chem. 2009, 74, 7804-11.

Lemal, D. M.; Ramanathan, S. "Fluorinated Three-Membered Ring Heterocycles," In Fluorinated Heterocyclic Compounds; Petrov, V. A., Ed.; Wiley: Hoboken, NJ, 2009; pp 3-64.

Lemal, D. M. "The Effect of Fluorine Substitution on Ring Inversion in Bicyclo[1.1.0]butanes," J. Org. Chem. 2009, 74, 2413-6.

Lemal, D. M.; Ramanathan, S.; Shellito, J. "o‑Fluoranil Chemistry: Diels-Alder versus Hetero-Diels-Alder Cycloaddition," J. Org. Chem. 2008, 73, 3392-6.

Ralli, P.; Zhang, Y.; Lemal, D. M. "Perfluorobarrelene," Tetrahedron Lett. 2008, 49, 7349-51.

Chen, X.; Lemal, D. M. “Functionalization of Saturated Fluorocarbons With and Without Light,” J. Fluorine Chem. 2006, 127, 1158-67.

Wei, Y.; Liu, Y.; Wong, T.; Lemal, D. M. “Extremely Facile Ring Inversion and Rearrangement in Fluorobicyclo[2.1.0]pentanes,” J. Fluorine Chem. 2006, 127, 688-703.

   Lemal, D. M. "Perspective on Fluorocarbon Chemistry," J. Org. Chem. 2004, 69, 1-11.

He, Y.; Junk, C. P.; Lemal, D. M. “A Remarkable Propellane,” J. Am. Chem. Soc. 2003, 125, 5590-1.

Lou, Y.; Chang, J.; Jorgensen, J.; Lemal, D. M. “Octachloroazulene,” J. Am. Chem. Soc. 2002, 124, 15302-15307.

Lemal, D. M. “Hexafluorobenzene Photochemistry: Wellspring of Fluorocarbon Structures”, Acc. Chem. Res. 2001, 34, 662-671.

Lemal, D. M. "Flogging the Fluorocarbons," In Fluorine Chemistry at the Millenium. Fascinated by Fluorine; Banks, R. E., Ed.; Elsevier Science: New York, 2000; Chap. 20.

Liu, Y.; Lemal, D. M. "Thermodynamics of a Diaminocarbene-Tetraaminoethylene Equilibrium," J. Am. Chem. Soc. 1999, 121, 10626.

Zhang, Y.; Smith, J.; Lemal, D. M. "Octafluorobicyclo[2.2.0]hex-1(4)-ene: A Greatly Strained Alkene with Novel Reactivity," J. Am. Chem. Soc. 1996, 118, 9454-5.

Correa, R. A.; Lindner, P. E.; Lemal, D. M. "Novel Keto-Enol Systems," J. Am. Chem. Soc. 1994, 116, 10795-6.

Takenaka, N. E.; Hamlin, R.; Lemal, D. M. "Hexafluorobenzene Oxide and Hexafluorooxepin," J. Am. Chem. Soc. 1990, 112, 6715-6.

Rahman, M. M.; Lemal, D. M.; Dailey, W. P. "Negative Hyperconjugation.  The Rotation-Inversion Barrier in a-Fluoramines," J. Am. Chem. Soc. 1988, 110, 1964-6.

Dailey, W. P.; Lemal, D. M. “Perfluorotropilidene Valence Isomers and the Perfluorotropylium Ion,” J. Am. Chem. Soc. 1984, 106, 1169.

Wirth, D.; Lemal, D. M. “A Cyclobutadiene Oxide (Dewar Furan),” J. Am. Chem. Soc. 1982, 104, 847.

Laganis, E. D.; Lemal, D. M. “5H-Perfluoropentamethylcyclopentadiene, An Extraordinary Carbon Acid,” J. Am. Chem. Soc. 1980, 102, 6633.


Grayston, M. W.; Saunders, W. D.; Lemal, D. M. “Perfluorocyclopentadienone,” J. Am. Chem. Soc. 1980, 102, 413.


Ross, J. A.; Seiders, R. P.; Lemal, D. M. “An Extraordinarily Facile Sulfoxide Rearrangement,” J. Am. Chem. Soc. 1976, 98, 4325.

Gerace, M. J.; Lemal, D. M.; Ertl, H. “Tetrafluorocyclobutadiene,” J. Am. Chem. Soc. 1975, 97, 5584.

Lemal, D. M.; Chao, P. “Sulfur Monoxide Chemistry.  The Nature of SO from Thiirane Oxide and the Mechanism of its Reaction with Dienes,” J. Am. Chem. Soc. 1973, 95, 922.

Lemal, D. M. “Aminonitrenes (1,1-Diazenes),” in "Nitrenes," Lwowski, W., Ed., John Wiley and Sons, Inc., 1970.

Lemal, D. M.; Staros, J. M.; Austel, V. “Valence Isomers of (CCF3)6,” J. Am. Chem. Soc. 1969, 91, 3373.

Lemal, D. M.; Lokensgard, J. P. “Hexamethylprismane,” J. Am. Chem. Soc.  1966, 88, 5934.

Lemal, D. M.; McGregor, S. D. “Dienes from 3-Pyrrolines.  A Stereospecific Deamination,” J. Am. Chem. Soc. 1966, 88, 1335.

Lemal, D. M.; Lovald, R. A.; Kawano, K. I. “Tetraaminoethylenes:  The Question of Dissociation,” J. Am. Chem. Soc. 1964, 86, 2518.

Lemal, D. M.; Menger, F.; Clark, G. “Bicyclobutane,” J. Am. Chem. Soc. 1963, 85, 2529.

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Jane E. G. Lipson

Tito, N.B.; Milner, S.T.; Lipson, Jane E.G. (2015) Enhanced Diffusion and Mobile Fronts in a Simple Lattice Model of Glass-Forming Liquids Soft Matter DOI 10.1039/c5sm01701g.

White, R.P.; Price, C.C.; Lipson, J.E.G. (2015) Effect of Interfaces on the Glass Transition of Supported and Freestanding Polymer Thin Films Macromolecules, 48, 4132-4141.

White, R.P.; Lipson, J.E.G. (2015) Free Volume in the Melt and How it Correlates with Experimental Glass Transition Temperatures: Results for a Large Set of Polymers ACS Macro Letters 4, 588-592.

Lipson, Jane E.G.; White, Ronald P. (2014) Connecting Theory and Experiment to Understand Miscibility in Polymer and Small Molecule Mixtures Journal of Chemical and Engineering Data 59, 3289-3300.

White, Ronald P.; Lipson, J.E.G. (2014) Free Volume, Cohesive Energy Density, and Internal Pressure as Predictors of Polymer Miscibility Macromolecules 47, 3959-3968.

DeFelice, Jeffrey; Lipson, Jane E.G. (2014) Polymer Miscibility in Supercritical Carbon Dioxide: Free Volume as a Driving Force Macromolecules 47, 5643-5654.

Tito, N.B.; Lipson, J.E.G.; Milner, S.T. (2013) Lattice Model of Mobility at Interfaces: Free Surfaces, Substrates, and Bilayers. Soft Matter, 9403-9413.

White, R.P.; Lipson, J.E.G.; (2013) Origins of Unusual Phase Behavior in Polymer/Ionic Liquid Solutions. Macromolecules, 46, 5714-5723.

Tito, N.B.; Lipson, J.E.G.; Milner, S.T. (2013) Lattice Model of Dynamic Heterogeneity and Kinetic Arrest in Glass-forming Liquids. Soft Matter, 9, 3173-3180.

White, R.P.; Lipson, J.E.G.; Higgins, J.S. (2012) How Pure Components Control Polymer Blend Miscibility. Macromolecules 45, 8861-8871.

Tito, N.B.; Lipson, J.E.G.; Milner, S.T. (2012) Ball-Of-Yarn Conformation of a Linear Gradient Copolymer in a Homopolymer Melt. Macromolecules, 45, 7607-7620.

Clark, E.A.; Lipson, J.E.G. (2012) LCST and UCST Behaviour in Polymer Solutions and Blends. Polymer, 53, 536-545.

White, R.P.; Lipson, J.E.G. (2011) Thermodynamic Treatment of Polymer Thin-Film Glasses. Physical Review E, 84, 041801.

Tito, N.B.; Lipson, J.E.G.; Milner, S.T. (2010) Self-Assembly of Lamellar Microphases in Linear Gradient Copolymer Melts. Macromolecules, 43, 10612-10620.

Lipson, J.E.G.; Milner, S.T. (2010) Delayed Glassification Model for Free-Surface Suppression of T-g in Polymer Glasses. Macromolecules, 43, 9865-9873.

Lipson, J.E.G.; Milner, S.T. (2010) Local and Average Glass Transitions in Polymer Thin Films. Macromolecules, 43, 9874-9880.

White, R. P.; Lipson, J.E.G; Higgins, J.S. (2010) Effects of Deuterium Substitution on the Physical Properties of Polymer Melts and Blends. Macromolecules, 43, 4287-4293.

Higgins, J.S.; White, R.P.; Lipson, J.E.G. (2010) A Simple Approach to Polymer Mixture Miscibility. Phil. Trans. A Roy. Soc. (350th anniversary issue), 368, 1009-1025.

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Glenn C. Micalizio

H. Mizoguchi, G. C. Micalizio “Convergent Synthesis of Angularly Substituted Trans-Decalins by a Metallacycle-mediated Cross-Coupling Reaction Cascade” Angew. Chem. Int. Ed. 2016, accepted.

G. C. Micalizio, N. F. O’Rourke, M. J. Kier “Metallacycle-mediated Cross-Coupling in Natural Product Synthesis” invited Report – Tetrahedron, 2016, accepted.

C. Aquino, S. N. Greszler, G. C. Micalizio “Access to the Cortistatin Pentacyclic Core by Alkoxide-Directed Metallacycle-Mediated Annulative Cross-Coupling” Org. Lett. 2016, 18, 2624-2627.

N. F. O'Rourke, G. C. Micalizio, "Cyclopropenes in Metallacycle-Mediated Cross-Coupling with Alkynes: Convergent synthesis of highly substituted vinylcyclopropanes" Org. Lett. 2016, 18, 1250-1253.

X. Cheng, G. C. Micalizio, "Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R,10S)-2-oxo-3,4-dehydroneomajucin, (2S)-hydroxy-3,4-dehydroneomajucin, and (–)-jiadifenin" J. Am. Chem. Soc. 2016, 138, 1150-1153.

H. Mizoguchi, G. C. Micalizio “Synthesis of Highly Functionalized Decalins via Metallacycle-Mediated Cross-Coupling” J. Am. Chem. Soc. 2015, 137, 6624-6628.

X. Cheng, G. C. Micalizio “An Annulation Reaction for the Synthesis of Cross-Conjugated Triene-containing Hydroindanes from Acyclic Precursors” Org. Lett. 2014, 16, 5144-5147.

V. Jeso, C. Aquino, X. Cheng, H. Mizoguchi, M. Nakashige, G. C. Micalizio, “Direct Synthesis of Angularly Substituted Trans-fused Hydroindanes by Convergent Coupling of Acyclic PrecursorsJ. Am. Chem. Soc. 2014, 136, 8209-8212.

V. Jeso, S. Iqbal, P. Hernandez, M. D. Cameron, H. Park, P. V. LoGrasso, G. C. Micalizio “Synthesis of Benzoquinone Ansamycin-Inspired Macrocyclic Lactams from Shikimic Acid” Angew. Chem. Int. Ed. 2013, 52, 4800-4804.

D. Yang, G. C. Micalizio “Synthesis of Alkaloid (–)-205B via Stereoselective Reductive Cross-Coupling and Intramolecular [3+2] Cycloaddition” J. Am. Chem. Soc. 2012, 134, 15237-15240.

S. Greszler, H. A. Reichard, G. C. Micalizio, “Asymmetric Synthesis of Dihydroindanes by Convergent Alkoxide-Directed Metallacycle-Mediated Bond Formation” J. Am. Chem. Soc. 2012, 134, 2766-2774.

M. Z. Chen, G. C. Micalizio “Three-Component Coupling Sequence for the Regiospecific Synthesis of Substituted Pyridines” J. Am. Chem. Soc. 2012, 134, 1352-1356.

C. Aquino, M. Sarkar, M. J. Chalmers, K. Mendez, T. Kodadek, G. C. Micalizio “A Biomimetic Polyketide-Inspired Approach to Small Molecule Ligand Discovery” Nature Chem. 2012, 4, 99-104.

D. Yang, G. C. Micalizio, “Convergent and Stereodivergent Synthesis of Complex 1-Aza-7-Oxabicyclo[2.2.1]heptanes” J. Am. Chem. Soc. 2011, 133, 9216-9219.

M. A. Tarselli, K. M. Raehal, A. K. Brasher, C. Groer, M. D. Cameron, L. M. Bohn, G. C. Micalizio, “Synthesis of Conolidine, a Potent Non-Opioid Analgesic for Tonic and Persistent Pain” Nature Chem. 2011, 3, 449-453.

V. Jeso, G. C. Micalizio, “Total Synthesis of Lehualide B by Allylic Alcohol–Alkyne Reductive Cross-Coupling” J. Am. Chem. Soc. 2010, 132, 11422-11424.

D. P. Canterbury, G. C. Micalizio, “Polyketide Assembly by Alkene–Alkyne Reductive Cross-Coupling: Spiroketals Through the Union of Homoallylic Alcohols” J. Am. Chem. Soc. 2010, 132, 7602-7604.

T. K. Macklin, G. C. Micalizio, “Convergent and Stereospecific Synthesis of Skipped Polyenes and Polyunsaturated Fatty Acids” Nature Chem. 2010, 2, 638-643.

D. Yang, G. G. Micalizio, “A Convergent Stereoselective Synthesis of Quinolizidines and Indolizidines: Chemoselective Coupling of 2-Hydroxymethyl Substituted Allylic Silanes with Imines” J. Am. Chem. Soc. 2009, 131, 17548-17549.

Dale F. Mierke

Dale F. Mierke

Ahn KH, Bertalovitz, AC, Mierke DF, Kendall DA. (2009) Dual role of the second extracellular loop of the cannabinoid receptor 1: ligand binding and receptor localization. Mol Pharmacol. 76 833-42. PMID. 19643997

Thomas BE, Sharma S, Mierke DF, Rosenblatt M. (2009) Parathyroid Hormone (PTH) and PTH Antagonist Induce Different Conformational Changes in the PTHR1 Receptor. J Bone Miner Res. 24 925-34. PMID. 19063682

Ahn KH, Pellegrini M, Tsomaia N, Yatawara AK, Kendall DA, Mierke DF. (2009) Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices. Biopolymers 91565-73. PMID. 19274719

Thomas, B., Woznica, I., Mierke, DF, Wittelsberger, A., Rosenblatt, M (2008) Conformational changes in the PTH receptor associated with activation by agonist. Mol Endocrinol. 22 1154-62. PMID 18258686

Monahan, P., Thomas, B., Wittelsberger, A., Mierke, DF, Rosenblatt, M. (2008) Mapping peptide hormone-receptor interactions using a disulfide-trapping approach. Biochemistry.47 5889-95. PMID 18459800

Famous, KR, Kumarsian, V., Sadri-Kakili, G, Schmidt, HD, Mierke, DF, Cha, J., Pierce, C. (2008) Phosphorylation-dependent trafficking of GluR2-containing AMPA receptors in the nucleus accumbens plays a critical role in the reinstatement of cocaine seeking. J Neurosci., 28, 11061-70. PMID 18945913.

Assil-Kishawi I, Samra TA, Mierke DF, Abou-Samra AB. (2008) Residue 17 of sauvagine cross-links to the first transmembrane domain of corticotropin-releasing factor receptor 1 (CRFR1). J Biol Chem. 283, 35644-51. PMID 18955489

Wittelsberger, A., Mierke, DF, Rosenblatt, M (2008) Mapping ligand-receptor interfaces: approaching the resolution limit of benzophenone-based photoaffinity scanning. Chem. Biol. Drug Des. 71, 380-383.

Chatterjee, J.; Mierke, DF.; Kessler, H. (2008) Conformational preference and potential templates of N-methylated cyclic pentaalanine peptides. Chemistry. 14, 1508-17.

Mierke, DF, Mao, L., Pellegrini, M., Piserchio, A., Plati, J., Tsomia, N. (2007) Structural characterization of the parathyroid hormone receptor domains determinant for ligand binding. Biochem. Soc. Trans. 35, 721-725.

Stone, SR., Giragossian, C., Mierke, DF, Jackson, GE (2007) Further evidence for a C-terminal structural motif in CCK(2) receptor active peptide hormones. Peptides. 28, 2211-22.

Dugan AS, Gasparovic ML, Tsomaia N, Mierke DF, O'Hara BA, Manley K, Atwood WJ. (2007) Identification of amino acid residues in BK virus VP1 that are critical for viability and growth. J Virol. 81, 11798-808.

Stone, SR., Mierke, DF, Jackson, GE (2007) Evidence for a C-terminal structural motif in gastrin and its bioactive fragments in membrane mimetic media. Peptides. 28, 1561-71.

Yu, J., Lubinsky, D., Tsomia, N., Huang, Z., Taylor, L., Mierke, D.F., Navarro, J., Miraz, O., Polgar, P. (2007) Activation of ERK, JNK, Akt, and G-protein coupled signaling by hybrid angiotensin II AT1/bradykinin B2 receptors expressed in HEK-293 cells. J Cell Biochem. 101, 192-204.

Plati, J., Tsomia, N., Piserchio, A., Mierke, DF (2007) Structural features of parathyroid hormone receptor coupled to Galpha(s)-protein. Biophys J. 92, 535-40.

Wolde, M. Fellows, A., Cheng, J., Kivenson, A., Karlson, K., Piserchio, A., Mierke, D.F., Stanton, B.A., Guggino, W.B., Madden, D.R. (2007) Targeting CAL as a negative regulator of D508-CFTR cell-surface expression: An RNAi and structure-based mutagenetic approach. J Biol Chem. 282, 8099-109.

Wittelsberger, A, B E Thomas, D F Mierke, and M Rosenblatt, “Methionine Acts as a ‘Magnet’ in Photoaffinity Crosslinking Experiments,” Federation of European Biochemical Societies Letters , 580:7 (2006) 1872-1876.

D’antona, A M, K H Ahn, L Wang, D F Mierke, J Lucas-Lenard, and D A Kendall, “A Cannabinoid Receptor 1 Mutation Proximal to the DRY Motif Results in Constitutive Activity and Reveals Intramolecular Interactions Involved in Receptor Activation,” Brain Research , 1108:1 (2006) 1-11.

Heller, M, M Sukopp, N Tsomaia, M John, D F Mierke, B Reif, and H Kessler, “The Conformation of Cyclo(-D-Pro-Ala4-) as a Model for Cyclic Pentapeptides of the DL4 Type,” Journal of the American Chemical Society , 128:42 (2006) 13806-13814.

Piserchio, A, M Spaller, and D F Mierke, “Targeting the PDZ Domains of Molecular Scaffolds of Transmembrane Ion Channels,” The American Association of Pharmaceutical Scientists Journal , 8:2 (2006) E396-E401.

Gee, G V, A S Dugan, N Tsomaia, D F Mierke, and W J Atwood, “The Role of Sialic Acid in Human Polyomavirus Infections,” Glycoconjugate Journal , 23:1-2 (2006) 19-26.

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Katherine A. Mirica

Mitchell, H. T.; Smith, M. K.; Blelloch, N. D.; Van Citters, D. W.; Mirica, K. A.* "Polycyclic Aromatic Hydrocarbons as Sublimable Adhesives" Chem. Mater. 201729, 2788–2793.

Smith, M. K.; Jensen, K. E.; Pivak, P. A.; Mirica, K.A.* "Direct Self-Assembly of Conductive Nanorods of Metal-Organic Frameworks into Chemiresistive Devices on Shrinkable Polymer Films" Chem. Mater. 201628, 5264–5268.

Azzarelli, J. M.; Mirica, K. A.; Ravnsbæk, J. B.; Swager, T. M., “Wireless Gas Detection with a Smartphone via RF Communication” Proc. Nat. Acad. Sci. USA2014111, 18162–18166.

Mirica, K. A.; Azzarelli, J. M.; Weis, J. G.; Schnorr, J. M.; Swager, T. M., “Rapid Prototyping of Carbon-Based Chemiresistive Gas Sensors on Paper” Proc. Nat. Acad. Sci. USA2013110, E3265–E3270.

Mirica, K. A.; Weis, J. G.; Schnorr, J. M.; Esser, B.; Swager, T. M., “Mechanical Drawing of Gas Sensors on Paper” Angew. Chem. Int. Ed., 201251, 10740–10745.

Shapiro, N.D.; Mirica, K. A.; Soh, S.; Phillips, S. T.; Taran, O.; Mace, C. R.; Shevkoplyas, S. S.; Whitesides, G. M. “Measuring Binding of Protein to Gel-Bound Ligands Using Magnetic Levitation” J. Am. Chem. Soc.2012134, 5637–5646.

Mirica, K. A.; Lockett, M.R.; Snyder, P. W.; Shapiro, N. D.; Mack, E. T.; Nam, S.; Whitesides, G. M. “Selective Precipitation and Purification of Monovalent Proteins Using Oligovalent Ligands and Ammonium Sulfate” Bioconjugate Chem.201223, 293–299.

Mirica, K. A.; Ilievski, F.; Ellerbee, A. K.; Shevkoplyas, S. S.; Whitesides, G. M., “Using Magnetic Levitation for Three Dimensional Self-Assembly”, Adv. Mater., 2011, 23, 4134–4140.

Reches, M.; Mirica, K. A.; Dasgupta, R.; Dickey, M. D.; Whitesides, G. M., “Thread as a Matrix for Biomedical Assays” ACS Appl. Mater. Interfaces20102, 1722–1728.

Mirica, K. A.; Shevkoplyas, S. S.; Phillips, S. T.; Gupta, M., and Whitesides, G. M., “Measuring Densities of Solids and Liquids Using Magnetic Levitation: Fundamentals” J. Am. Chem. Soc.2009131, 10049–10058.

Mirica, K. A.; Phillips, S. T.; Shevkoplyas, S. S.; and Whitesides, G. M., “Using Magnetic Levitation to Distinguish Atomic-Level Differences in Chemical Composition of Polymers, and to Monitor Chemical Reactions on Solid Supports” J. Am. Chem. Soc.2008,130, 17678–17680. 


Maria Pellegrini

Bucur O, Gaidos G, Yatawara A, Pennarun B, Rupasinghe C, Roux J, Andrei S, Guo B, Panaitiu A, Pellegrini M, Mierke DF, Khosravi-Far R. "A novel caspase 8 selective small molecule potentiates TRAIL-induced cell death." Sci Rep. 2015 May 11;5:9893. doi: 10.1038/srep09893. PMID: 25962125

Song GJ, Leslie KL, Barrick S, Mamonova T, Fitzpatrick JM, Drombosky KW, Peyser N, Wang B, Pellegrini M, Bauer PM, Friedman PA, Mierke DF, Bisello A. "Phosphorylation of Ezrin-Radixin-Moesin-binding Phosphoprotein 50 (EBP50) by Akt Promotes Stability and Mitogenic Function of S-phase Kinase-associated Protein-2 (Skp2)." J Biol Chem. 2015 290(5):2879-87.  doi: 10.1074/jbc.M114.609768. PMID: 25492869

Yatawara A, Gaidos G, Rupasinghe CN, O'Hara BA, Pellegrini M, Atwood WJ, Mierke DF. "Small-molecule inhibitors of JC polyomavirus infection." J Pept Sci. 2014 doi: 10.1002/psc.2731. PMID: 25522925

Guo B, Audu CO, Cochran JC, Mierke DF, Pellegrini M. Protein Engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKβ binding. Biochemistry. 2014 53(43):6776-85. PMID: 25286246 DOI:10.1021/bi500861x

Guo B, Gurel PS, Shu R, Higgs HN, Pellegrini M, Mierke DF.Monitoring ATP hydrolysis and ATPase inhibitor screening using (1)H NMR. Chem Commun (Camb). 2014 Sep 6;50(81):12037-9. doi: 10.1039/c4cc04399e. PMID: 25170530

Fitzpatrick JM, Pellegrini M, Cushing PR, Mierke DF. Small Molecule Inhibition of the Na+/H+ Exchange Regulatory Factor 1 and Parathyroid Hormone 1 Receptor Interaction. Biochemistry. 2014 ;53(37):5916-22. PMID: 25171053

Audu CO, Plati JJ, Pellegrini M, Mierke DF. Engineering a soluble parathyroid hormone GPCR mimetic. Proteins. 2014 Jul;82(7):1370-5. doi: 10.1002/prot.24503. Epub 2014 Jan 15.

Audu, C. O.; Cochran, J. C.; Pellegrini, M.; Mierke, D. F. Recombinant Production of TEV Cleaved Human Parathyroid Hormone. (2013) Journal of Peptide Science, 19, 504–510. PMCID:PMC3755510

Pellegrini M, Willen L, Perroud M, Krushinskie D, Strauch K, Cuervo H, Day ES, Schneider P, Zheng TS.: Structure of the extracellular domains of human and xenopus Fn14: Implications in the evolution of TWEAK and Fn14 interactions. FEBS J. 2013 Apr;280(8):1818-29

Audu CO, O'Hara B, Pellegrini M, Wang L, Atwood W, Mierke DF. Reigning in Polyoma Virus associated nephropathy: design and characterization of a template mimicking BK Viral Coat Protein cellular binding. Biochemistry, 2012 51 (41): 8092-8099. NIHMS412129

Cushing PR, Vouilleme L, Pellegrini M, Boisguerin P, Madden DR. A stabilizing influence: CAL PDZ inhibition extends the half-life of F508-CFTR. Angew Chem Int Ed Engl. 2010 Dec 17;49(51):9907-11. PMCID: PMC3033200.

Lowden, MJ, Skorupski, K, Pellegrini, M, Chiorazzo, MG, Taylor, RK., and Kull, FJ. Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. PNAS 2010, 107:2860-65 PMCID: PMC284031.

Ahn KH, Pellegrini M, Tsomaia N, Yatawara AK, Kendall DA, Mierke DF Structural analysis of the human cannabinoid receptor one carboxyl-terminus identifies two amphipathic helices. Biopolymers. 2009 91(7):565-73. PMCID:PMC2698224

Rushe M, Silvian L , Bixler S, Chen LL, Cheung A, Bowes S, Cuervo H, Berkowitz S, Zheng T, Guckian K, Pellegrini M, Lugovskoy A. "Structure of a NEMO/IKK-associating domain reveals architecture of the interaction site." Structure 2008 16:798-808

Baker DP, Lin EY, Lin K, Pellegrini M, Petter RC, Chen LL, Arduini RM, Brickelmaier M, Wen D, Hess DM, Chen L, Grant D, Whitty A, Gill A, Lindner DJ, Pepinsky RB. "N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model." Bioconjug. Chem. 2006 17:179-88.

Seck T, Pellegrini M, Florea AM, Grignoux V, Baron R, Mierke DF, Horne WC. "The delta e13 isoform of the calcitonin receptor forms a six-transmembrane domain receptor with dominant-negative effects on receptor surface expression and signaling." Mol. Endocrinol. 2005 19:2132-44.

Cusack KP, Arnold LD, Barberis CE, Chen H, Ericsson AM, Gaza-Bulseco GS, Gordon TD, Grinnell CM, Harsch A, Pellegrini M, Tarcsa E. "A 13C NMR approach to categorizing potential limitations of alpha,beta-unsaturated carbonyl systems in drug-like molecules." Bioorg. Med. Chem. Lett. 2004 14:5503-7.

Pellegrini M, Bremer AA, Ulfers AL, Boyd ND, Mierke DF. "Molecular characterization of the substance P/neurokinin-1 receptor complex: development of an experimentally based model." J. Biol. Chem. 2001 276:22862-7 .

Pellegrini M, Liehr S, Fisher AL, Laub PB, Cooperman BS, Mierke DF. "Structure-based optimization of peptide inhibitors of mammalian ribonucleotide reductase." Biochemistry 2000 39:12210-5.

Pellegrini M, Mierke DF. "Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy." Biochemistry 1999 38:14775-83.

Pellegrini M, Bisello A, Rosenblatt M, Chorev M, Mierke DF. "Binding domain of human parathyroid hormone receptor: from conformation to function." Biochemistry 1998 37:12737-43.

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Ekaterina V. Pletneva

Ekaterina V. Pletneva

J. F. Amacher, F. Zhong, G. P. Lisi, M. Q., Zhu, S. L. Alden, K. R. Hoke, D. R. Madden,  E. V. Pletneva “A Compact Structure of Cytochrome c Trapped in a Lysine-Ligated State: Loop Refolding and Functional Implications of a Conformational Switch” J. Am. Chem. Soc. 2015, 137, 8435–8449.

C. W. T. Leung, Y. Hong, J. Hanske, E. Zhao, S. Chen, E. V. Pletneva, B. Z. Tang "A superior fluorescent probe for detection of cardiolipin" Anal. Chem. 2014, 86, 1263-8.

J. Gu, S. Yang, A. J. Rajic, I. V. Kurnikov, T. R. Prytkova, E. V. Pletneva "Control of cytochrome c redox reactivity through intraprotein hydrogen-bonding network" Chem. Commun. 2014, 50, 5355-5357.

F. Zhong, G. P. Lisi, D. P. Collins, J. H. Dawson, E. V. Pletneva "Redox-dependent stability, protonation, and reactivity of cysteine-bound heme proteins" Proc. Natl. Acad. Sci. U. S. A. 2014, 111, E306-15.

J. Muenzner, J. R. Toffey, Y. Hong, E. V. Pletneva "Becoming a peroxidase: cardiolipin-induced unfolding of cytochrome c" J. Phys. Chem. B 2013, 117, 12878-12886.

E. J. Snider, J. Muenzner, J. R. Toffey, Y. Hong, E. V. Pletneva "Multifaceted effects of ATP on cardiolipin-bound cytochrome c" Biochemistry 2013, 52, 993-995.

A. J. Vincelli, D. S. Pottinger, F. Zhong, J. Hanske, S. G. Rolland, B. Conradt, E. V. Pletneva "Recombinant expression, biophysical characterization, and cardiolipin-induced changes of two Caenorhabditis elegans cytochrome c proteins" Biochemistry 2013, 52, 653-666.

Y. Hong, J. Muenzner, S. K. Grimm, E. V. Pletneva "Origin of the conformational heterogeneity of cardiolipin-bound cytochrome c" J. Am. Chem. Soc. 2012, 134, 18713-18723.

T. L. Freeman, Y. Hong, K. H. Schiavoni, D. M. I. Bandara, E. V. Pletneva “Changes in the heme ligation during folding of a Geobacter sulfurreducens sensor GSU0935” Dalton. Trans. 2012, 41, 8022-8030.

J. Hanske, J. R. Toffey, A. M. Morenz, A. J. Bonilla, K. H. Schiavoni, E. V. Pletneva “Conformational properties of cardiolipin-bound cytochrome cProc. Natl. Acad. Sci. U. S. A. 2012, 109, 125-30.

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Michael J. Ragusa

RE Stanley, MJ Ragusa, JH Hurley. The beginning of the end: How scaffolds and coalescing vesicles nucleate autophagosome biogenesis. Trends in Cell Biology 2014; 24: 73-81.

C Jao*, MJ Ragusa*, RE Stanley, JH Hurley. A HORMA domain in Atg13 mediates PI 3-kinase recruitment in autophagy. Proceedings of the National Academy of Sciences 2013; 110: 5486-5491. *These authors contributed equally to the work

MJ Ragusa*, RE Stanley*, JH Hurley. Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis. Cell 2012; 151: 1501-1512. *These authors contributed equally to the work

S Baskaran, MJ Ragusa, E Boura, JH Hurley. Two-Site Recognition of Phosphatidylinositol 3-Phosphate by PROPPINs in Autophagy. Molecular Cell 2012; 47: 339-348.

B Dancheck*, MJ Ragusa*, M Allaire, AC Nairn, R Page, W Peti. Molecular Investigations of the Structure and Function of the Protein Phosphatase 1:Spinophilin:Inhibitor-2 Heterotrimeric Complex. Biochemistry 2011; 50: 1238-1246. *These authors contributed equally to the work

MJ Ragusa, M Allaire, AC Nairn, R Page, W Peti. Flexibility in the PP1:spinophilin holoenzyme. FEBS Letters 2011; 585: 36-40.

MJ Ragusa, B Dancheck, DA Critton, AC Nairn, R Page, W Peti. Spinophilin directs protein phosphatase 1 specificity by blocking substrates binding sites. Nature Structural and Molecular Biology 2010; 17: 459-464.

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Roger H. Soderberg

Galasyn, J.F.; Hornig, J.F. and Soderberg, R.H. "The Loss of PAH from Quartz Fiber Filters", APCA Journal 34, 57 (1984).

Barefoot, A.C. (III); Galasyn, J.F.; Hornig, J.F. and Soderberg, R.H. "Woodsmoke Analysis: Vaporization Losses of PAH from Filters, and Levo-glucosan as a Distinctive Marker for Woodsmoke", Polynucl. Aromatic Hydrocarbons, M. Cooke, ed., Battelle Press, Columbus, OH; (1984).

Barefoot, A.C. (III); Hornig, J.F.; Parravano, C. and Soderberg, R.H. "Impact of Residential Wood Burning on Ambient Air Quality", Measurement and Monitoring of Non-Criteria (Toxic) Contaminants in Air, Air Pollution Control Association (1983).


Thomas A. Spencer

“Carbocation-π Interaction: Evaluation of the Stabilization by Phenylalanine of a Biochemical Carbocation Intermediate", Ditchfield, R.; Spencer, T.A.  Org. Biomol. Chem.  2016, 14, 9543-9548

"Carbocation-π Interaction: The 1,1 - Dimethylallyl Cation and Benzene", Ditchfield, R.; Spencer, T.A. Tetrahedron Lett., 2011, 52, 3674-3677

"Bridged Aromatic Alkenes for the Study of Carbocation-π Interaction", Spencer, T.A.; Popovici-Müller, J,; van Beusichem, B; Viscardi MacMillan, C.; Lavey, C.F.; Sin, J.M.; Ditchfield, R.  Tetrahedron, 2010, 66, 4441-4451.

"Synthesis of Benzophenone-Containing Fatty Acids", Gan, Y.; Wang, P.; Spencer, T.A. J.Org. Chem., 2006, 71, 9487-9490.

"Cholesterol Surrogates Incorporating a Benzophene as Part of the Sterol Tetracycle", Gan, Y.; Spencer, T.A.  J.Org. Chem., 2006, 71, 5870-5875.

"Neonsteroidal Benzophenone-Containing Analogs of Cholesterol", Gan, Y.; Blank, D.H.; Ney, J.E.; Spencer, T.A.  J.Org. Chem., 2006, 71, 5864-5669.

"Preparation and Biochemical Evaluation of Fluorenone-Containing Lipid Analogs", Spencer, T.A.; Wang, P.; Popovici-Mueller, J.V.; Pelltan, ID.; Fielding, P.E.; Fielding, C.J.  Bioorg. Med. Chem. Lett., 2006, 16, 3000-3004.

"Molecular Mechanism of Reverse Cholesterol Transport: Reaction of Pre-B- Migrating High-Density Lipoprotein with Plasma Lecithin/Cholesterol Acyltransferase", Nakamura, Y.; Kotite, L.; Gan, Y.; Spencer, T.A.; Fielding, C.J.; Fielding, P.E. Biochemistry, 2004, 43, 14811-14820.

"Benzophenone-Containing Cholesterol Surrogates: Synthesis and Biological Evaluation", Spencer, T.A.; Wang, P.; Li, D.; Russel, J.S.; Blank, D.H.; Fielding, P.E.; Fielding, C.J.  Lipid Res., 2004, 45, 1510-1518.

"Synthesis of Benzophenone-Containing Analogues of Phosphatidylcholine:, Wang, P.;Blank, D.H.; Spencer, T.A.  J.Org. Chem., 2004, 69, 2693-2702.

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Dean E. Wilcox

George P. Lisi, Russell P. Hughes, Dean E. Wilcox, “Coordination Contributions to Protein Stability in Metal-Substituted Carbonic Anhydrase”, Journal of Biological Inorganic Chemistry, 2016 21, 659-667.

Marcelo M. Pedroso, Fernanda Ely, Natasa Mitic, Margaret C. Carpenter, Lawrence R. Gahan, Dean E. Wilcox, James L. Larrabee, David L. Ollis, Gerhard Schenk, “Comparative investigation of the reaction mechanisms of the organophosphate-degrading phosphotriesterases from Agrobacterium radiobacter (OpdA) and Pseudomonas diminuta (OPH)”, Journal of Biological Inorganic Chemistry 2014 19, 1263-1275.

George P. Lisi, Chien Y. M. Png, Dean E. Wilcox, “Thermodynamic Contributions to the Stability of the Insulin Hexamer”, Biochemistry 2014 53, 3576-3584.

Margaret C. Carpenter and Dean E. Wilcox, “Thermodynamics of Formation of the Insulin Hexamer: Metal-Stabilized Proton-Coupled Assembly of Quaternary Structure”, Biochemistry 2014 53, 1296-1301.

Nicholas E. Grossoehme, Scott B. Mulrooney, Robert P. Hausinger, Dean E. Wilcox “Thermodynamics of Ni2+, Cu2+, and Zn2+ Binding to the Urease Metallochaperone UreE” Biochemistry 2007 46, 10506-10516.

Ruiguang Ge, Yi Zhang, Xuesong Sun, Rory M. Watt, Qing-Yu He, Jian-Dong Huang, Dean E. Wilcox, Hongzhe Sun “Thermodynamic and Kinetic Aspects of Metal Binding to the Histidine-Rich Protein, Hpn” Journal of the American Chemical Society 2006 128, 11330-11331.

Nicholas E. Grossoehme, Shreeram Akilesh, Mary Lou Guerinot, Dean E. Wilcox, " Metal Binding Thermodynamics of the Histidine-Rich Sequence from the Iron Transport Protein ITR1 from Arabidopsis thaliana", Inorganic Chemistry 2006 45, 8500-8508; 8812. 

Yi Zhang and Dean E. Wilcox, "Thermodynamic and Spectroscopic Study of Cu(II) and Ni(II) Binding to Bovine Serum Albumin" Journal of Biological Inorganic Chemistry, 2002 7, 327-337.

M. C. Carpenter, A. Shami Shah, S. DeSilva, A. Gleaton, A. Su, B. Goundie, M. L. Croteau, M. J. Stevenson, D. E. Wilcox, R. N. Austin, “Calorimetric Studies of Pb(II) and Zn(II) Binding to MT-3, a Neurologically Important Metallothionein”, Metallomics 2016 8, 605-617.

Anne M. Rich, Elisa Bombarda, Austin D. Schenk, Paul E. Lee, Elizabeth H. Cox, Anne M. Spuches, Lynn D. Hudson, Bruno Keifer, Dean E. Wilcox, "Thermodynamics of Zn2+ Binding to Cys2His2 and Cys2HisCys Zinc Fingers and a Cys4 Transcription Factor Site", Journal of the American Chemical Society 2012 134, 10405-10418.

Anne M. Spuches and Dean E. Wilcox, "Monomethylarsenite Competes with Zn2+ for Binding Sites in the Glucocorticoid Receptor", Journal of the American Chemical Society 2008 130, 8148-8149.

Colette F. Quinn, Margaret C. Carpenter, Molly L. Croteau, Dean E. Wilcox, “Isothermal Titration Calorimetry of Metal Ions Binding to Proteins”, Methods in Enzymology, Vol. 567, Andrew Feig, Ed., Burlington: Academic Press, 2016, pp. 3-21.

Destinee K. Johnson, Michael J. Stevenson, Zayed A. Almadidy, Sharon E. Jenkins, Dean. E. Wilcox, Nicholas E. Grossoehme, “Stabilization of Cu(I) for Binding and Calorimetric Measurements in Aqueous Solution”, Dalton Transactions 2015 44, 16494-16505.

Nicholas E. Grossoehme, Anne M. Spuches, Dean E. Wilcox, “Application of Isothermal Titration Calorimetry in Bioinorganic Chemistry”, Journal of Biological Inorganic Chemistry 2010 15, 1183-1191, 1193.

Yi Zhang, Shreeram Akilesh, Dean E. Wilcox, "Isothermal Titration Calorimetry Measurements of Ni(II) and Cu(II) Binding to His, GlyGlyHis, HisGlyHis and Bovine Serum Albumin: A Critical Evaluation" Inorganic Chemistry 2000 39, 3057-3064.

Xiaoming He, Steven G. Swarts, Eugene Demidenko, Ann B. Flood, Oleg Grinberg Jiang Gui, Michael Mariani, Stephen D. Marsh, Andres E. Ruuge, Jason W. Sidabras, Dmitry Tipikin, Dean E. Wilcox, Harold M. Swartz, “Development and Validation of an Ex Vivo Electron Paramagnetic Resonance Fingernail Biodosimetric Method”, Radiation Protection Dosimetry 2014 159, 172-181.

Xiaoming He, Jiang Gui, Thomas P. Matthews, Benjamin B. Williams, Steven G. Swarts, Oleg Grinberg, Jason Sidabras, Dean E. Wilcox, Harold M. Swartz, “Use of fingernails and toenails for triage dosimetry of large populations after potential exposure to ionizing radiation”, Radiation Measurements 2011 46, 882-887.

Dean E. Wilcox, Xiaoming He, Jiang Gui, Andres E. Ruuge, Hongbin Li, Benjamin B. Williams, Harold M. Swartz, “Dosimetry Based on EPR Spectral Analysis of Fingernail Clippings”, Health Physics Journal 2010 98, 309-317.

Oleg Y. Grinberg, Benjamin B. Williams, Andres E. Ruuge, Stalina A. Grinberg, Dean E. Wilcox, Harold M. Swartz, Jack H. Freed, “Oxygen Effects on the EPR Signals from Wood Charcoals: Experimental Results and a New Model”, Journal of Physical Chemistry B 2007 111, 13316-13324.

Harriet Kruszyna, John S. Magyar, Lori G. Rochelle, Michael A. Russell, Roger P. Smith, Dean E. Wilcox, “Spectroscopic Studies of Nitric Oxide (NO) Interactions with Cobalamins: Reaction of NO with Superoxocobalamin(III) Likely Accounts for Cobalamin Reversal of the Biological Effects of NO” Journal of Pharmacology and Experimental Theraputics 1998 285, 665-671.

Louis R. Cantilena Jr., Roger P. Smith, Susan Frasur, Harriet Kruszyna, Robert Kruszyna, Dean E. Wilcox, "Nitric Oxide Hemoglobin in Patients Receiving Nitroglycerin as Detected by Electron Paramagnetic Resonance Spectroscopy" The Journal of Laboratory and Clinical Medicine 1992 120, 902-907.

Dean E. Wilcox, Harriet Kruszyna, Robert Kruszyna, Roger P. Smith, "Effect of Cyanide on the Reaction of Nitroprusside with Hemoglobin: Relevance to Cyanide Interference with the Biological Activity of Nitroprusside" Chemical Research in Toxicology 1990 3, 71-76.

Robert Kruszyna, Harriet Kruszyna, Roger P. Smith, C. Dennis Thron, Dean E. Wilcox, "Nitrite Conversion to Nitric Oxide in Red Cells and Its Stabilization as a Nitrosylated Valency Hybrid of Hemoglobin" Journal of Pharmacology and Experimental Therapeutics 1987 241, 307-313.

Dean E. Wilcox, Laura L. Bennett, Elizabeth H. Cox, George Haleblian, Brian T. Hill, Eric P. Kowack, Xiaoyan Liu, Jane S. Merkel, Amy E. Palmer, Matthew C. Posewitz, Joann E. Roy, Karen E. Wetterhahn, "Interaction of Metallothionein with the Carcinogenic Metals Ni(II), Cr(VI) and As(III)" Metallothionein IV, C. D. Klaassen (Ed.); Birkhäuser, Basel, 1999; pp. 585-594.

Yin Xu and Dean E. Wilcox, "Oxidation of Zinc Finger Cysteines to Thiolsulfinate" Journal of the American Chemical Society 1998 120, 7375-7376.

Matthew C. Posewitz and Dean E. Wilcox, “Properties of the Sp1 Zinc Finger #3 Peptide: Coordination Chemistry, Redox Reactions and Metal Binding Competition with Metallothionein” Chemical Research in Toxicology 1995 8, 1020-1028.

William B. Jones, Timothy E. Elgren, Maurice M. Morelock, R. C. Elder, Dean E. Wilcox, "Technetium Metallothionein:  A Spectroscopic and EXAFS Study of 99TcO+3 Binding to Zn7-Metallothionein" Inorganic Chemistry 1994 33, 5571-5578.

F. Jon Kull, Michael F. Reed, Timothy E. Elgren, Thomas L. Ciardelli, Dean E. Wilcox, "Solid Phase Peptide Synthesis of the a and b Domains of Human Liver Metallothionein and the Neurospora crassa Metallothionein", Journal of the American Chemical Society 1990 112, 2291-2298.

Joseph A. Barrera and Dean E. Wilcox, "EPR Study of the Toluene Solution Properties of the Chromium(III)-Alkyl Complexes [CpCrMeCl]2, [Cp*CrRCl]2 (R = Me, Et, CH2SiMe3) and [Cp*CrMeBr]2: Dimer-Monomer Equilibria in Solution”, Inorganic Chemistry 1992 31, 1745-1752.

Dean E. Wilcox, “Binuclear Metallohydrolases” Chemical Reviews 1996 96, 2435-2458.

Shengke Wang, Mann H. Lee, Robert P. Hausinger, Patrick A. Clark, Dean E. Wilcox, Robert A. Scott, "Structure of the Dinuclear Active Site of Urease. X-Ray Absorption Spectroscopic Study of Native and 2-Mercaptoethanol-Inhibited Bacterial and Plant Enzymes", Inorganic Chemistry 1994 33, 1589-1593.

Michael G. Finnegan, Andrzej T. Koval, Mark T. Werth, Patrick A. Clark, Dean E. Wilcox, Michael K. Johnson, "Variable Temperature Magnetic Circular Dichroism Spectroscopy as a Probe of the Electronic and Magnetic Properties of Nickel in Jack Bean Urease" Journal of the American Chemical Society 1991 113, 4030-4032.

Patrick A. Clark, Dean E. Wilcox, Robert A. Scott, "X-ray Absorption Spectroscopic Evidence for Direct Ni-S Bonding and New Ni-Ni Interaction Upon Binding of the Competitive Inhibitor 2-mercaptoethanol to Jackbean Urease", Inorganic Chemistry 1990 29, 579-581.

Patrick A. Clark and Dean E. Wilcox, "Magnetic Properties of the Nickel Enzymes Urease, Ni-substituted Carboxypeptidase A and Ni-substituted Carbonic Anhydrase" Inorganic Chemistry 1989 28, 1326-1333.

Sylvie R. Desjardins, Dean E. Wilcox, Ronald L. Musselman, Edward I. Solomon, "Polarized, Single Crystal, Electronic Spectral Studies of Cu2Cl6-2:  Excited-State Effects of the Binuclear Interaction" Inorganic Chemistry 1987 26, 288-300.

Dean E. Wilcox, Arturo G. Porras, Yeong T. Hwang, Konrad Lerch, Marjorie E. Winkler, Edward I. Solomon,"Substrate Analogue Binding to the Coupled Binuclear Copper Active Site in Tyrosinase" Journal of the American Chemical Society 1985 107, 4015-4027.

T. David Westmoreland, Dean E. Wilcox, Michael J. Baldwin, William B. Mims, Edward I. Solomon, "Detailed Spectral Analysis of Half-Met Hemocyanins: Mixed-Valent Contributions to Electronic Properties and Structure" Journal of the American Chemical Society 1989 111, 6106-6123.

Dean E. Wilcox, John R. Long, Edward I. Solomon, "EPR Studies of the  'EPR- nondetectable' Met Derivative of Hemocyanin:  Perturbations and Displacement of the Endogenous Bridge in the Coupled Binuclear Copper Active Site" Journal of the American Chemical Society 1984 106, 2186-2194.

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John Sterling Winn

John Sterling Winn

Infrared Spectra of OCS Monomer and Clusters in Solid Parahydrogen, J. Chem. Phys., in preparation (with B. B. Smith and R. Ditchfield).

Novel Preparation and Characterization of Doped Parahydrogen Solids, Rev. Sci. Inst., in preparation (with B. B. Smith).

Selecting Exciting Topics for Students of Twenty-First Century Physical Chemistry (为21世纪的学生选择有趣的物理化学 课题), Proceedings of the 2nd University Fundamental Courses Forum on Chemistry and Chemical Engineering, Wuhan, China (Higher Education Press, China, 2007).

Lineshape Analysis of CO in Kr and Xe Matrices (with P. Hu), Phys. Chem. Letters, in preparation.

Infrared Spectrum of Matrix-Isolated CO and CO Photoproduct from OCS Photolysis, J. of Phys. Chem. A, 104, 3472 (2000). (with D. T. Anderson)

Physical Chemistry (HarperCollins, New York, 1995).

Matrix Isolated HF: the High-Resolution Infrared Spectrum of a Cryogenically Solvated Hindered Rotor, Chem. Phys. 189, 171 (1994). (with D. T. Anderson)

The effect of solvent configuration on matrix-isolation solute lineshapes. J. Chem. Phys. 94, 5275 (1991).

Matrix-isolated OCS: The high resolution IR spectra of a cryogenically solvated linear molecule. J. Chem. Phys. 94, 5270 (1991). (with V. I. Lang)

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Jimmy Wu

"Transition Metal-Free C3 Arylation of Indoles with Aryl Halides" Chen, J.; Wu, J Angew. Chem. Int. Ed. 201756, Early View.

“Stereoselective Synthesis and Biological Evaluation of C1-Epimeric and Desmethyl Monomeric Nuphar Analogues” Li, H.; Cooke, T. J.; Korotkov, A.; Chapman, C. W.; Eastman, A.; Wu, J. J. Org. Chem. 201782, ASAP.

“Synthetic Small Molecule GLP-1 Secretagogues Prepared by Means of a Three-Component Indole Annulation Strategy” Chepurny, O. G.; Leech, C. A.; Tomanik, M.; DiPoto, M. C.; Li, H.; Han, X.; Meng, Q.; Cooney, R. N.; Wu, J.; Holz, G. G. Sci. Rep. 2016, 28934.

“Enantioselective Formal Syntheses of 11 Nuphar Alkaloids and Discovery of Potent Apoptotic Monomeric Analogues” Li, H.; Korotkov, A.; Chapman, C. W.; Eastman, A.; Wu, J. Angew. Chem. Int. Ed. 2016, 55, 3509−3513.

“Dearomative Indole (3+2) Reactions with Azaoxyallyl Cations − New Method for the Synthesis of Pyrroloindolines” DiPoto, M. C.; Hughes, R. P.; Wu, J. J. Am. Chem. Soc. 2015, 137, 14861-14864.

“Vinylogous Mukaiyama−Michael Reactions of Dihydropyridinones” Li, H.; Wu, J. Org. Lett. 2015, 17, 54245427.

“Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids” Korotkov, A.; Li, H.; Chapman, C. W.; Xue, H.; MacMillan, J. B.; Eastman, A.; Wu, J. Angew. Chem. Int. Ed. 2015, 54, 10604-10607.

"Regioselective Formal Hydroamination of Styrenes with 1-Phenyl-1H-tetrazole-5-thiol" Savolainen, M. A.; Han, X.; Wu, J. Org. Lett. 201416, 4349−4351.

“Dearomative Indole (3+2) Cycloaddition Reactions” Li, H.; Hughes, R. P.; Wu, J. J. Am. Chem. Soc. 2014136, 62886296

"Markovnikov-Selective Hydrothiolation of Styrenes: Application to the Synthesis of Stereodefined Trisubstituted Olefins" Savolainen, M. A.; Wu, J. Org. Lett. 201315, 38023804.

"Redox Chain Reaction - Indole and Pyrrole Alkylation with Unactivated Secondary Alcohols" Han, X.; Wu, J. Angew. Chem. Int. Ed. 2013, 52, 4637−4640.

"Ga(III)-Catalyzed Three-Component (4+3) Cycloaddition Reactions" Han, X.; Li, H.; Hughes, R. P.; Wu, J. Angew. Chem. Int. Ed. 2012, 51, 10390−10393.

"Palladium-Catalyzed Allylic Fluorination of Cinnamyl Phosphorothioate Esters" Lauer, A. M.; Wu, J. Org. Lett. 2012, 14, 5138−5141.

"Phosphorothioic Acids as Surrogates for H2S - Synthesis of Chiral Tetrahydrothiophenes" Robertson, F. J.; Wu, J. J. Am. Chem. Soc. 2012, 134, 2775−2780.

"Cu(I)-Catalyzed, alpha-Selective, Allylic Alkylation Reactions between Phosphorothioate Esters and Organomagnesium Reagents" Lauer, A. M.; Mahmud, F.; Wu, J. J. Am. Chem. Soc. 2011, 133, 9119−9112. (This report was highlighted in Synfacts 2011, 9, 1009.)

"Direct Annulation and Alkylation of Indoles with 2-Aminobenzyl Alcohols Catalyzed by TFA” Robertson, F. J.; Kenimer, B. D.; Wu, J. Tetrahedron 2011, 67, 4327−4332. (Invited Contribution - Symposium in Print: Tetrahedron Young Investigators Award for Prof. Dean Toste)

"Ga(OTf)3-Catalyzed Direct Substitution of Alcohols with Sulfur Nucleophiles” Han, X.; Wu, J. Org. Lett. 2010, 12, 5780−5782.

"Convenient Synthesis of Allylic Thioethers from Phosphorothioate Esters and Alcohols” Robertson, F. J.; Wu, J. Org. Lett. 2010, 12, 2668−2671.

"Mild Two-Step Process for the Transition-Metal-Free Synthesis of Carbon−Carbon Bonds from Allylic Alcohols/Ethers and Grignard Reagents” Han, X.; Zhang, Y.; Wu, J. J. Am. Chem. Soc. 2010, 132, 4104−4106. (This report was highlighted in Synfacts 2010, 6, 700.)

"(3+2)-Cycloaddition Reactions of Oxyallyl Cations” Li, H.; Wu, J. Synthesis 2015, 47, 22−33.

"Review of Recent Advances in Nucleophilic C-F Bond-forming Reactions" Wu, J. Tetrahedron Lett. 201455, 4289–4294

"Diethylphosphorothioic Acid" Wu, J. Encyclopedia of Reagents for Organic Synthesis2014, DOI: 10.1002/047084289X.rn01667

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