Katherine A. Mirica

Assistant Professor of Chemistry

The research in the Mirica Group focuses on addressing global challenges in healthcare and environmental stewardship through innovations in Materials Chemistry.  The experimental strategy emphasizes molecular design and synthesis of responsive materials compatible with the unique demands of low-power, portable, affordable, easy-to-use electronic sensing devices.  An important aspect of research in the group is a feedback loop between fundamental and applied science, where the fundamental understanding of interactions of small molecules with responsive materials is used, probed, and refined in functional devices.  Materials and methods developed in the group may also be applicable to information storage, and energy storage, conversion, and catalysis.

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Department:
Chemistry
Education:
B.S. Boston College
Ph.D. Harvard University

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Selected Publications

Mitchell, H. T.; Smith, M. K.; Blelloch, N. D.; Van Citters, D. W.; Mirica, K. A.* "Polycyclic Aromatic Hydrocarbons as Sublimable Adhesives" Chem. Mater. 201729, 2788–2793.

Smith, M. K.; Jensen, K. E.; Pivak, P. A.; Mirica, K.A.* "Direct Self-Assembly of Conductive Nanorods of Metal-Organic Frameworks into Chemiresistive Devices on Shrinkable Polymer Films" Chem. Mater. 201628, 5264–5268.

Azzarelli, J. M.; Mirica, K. A.; Ravnsbæk, J. B.; Swager, T. M., “Wireless Gas Detection with a Smartphone via RF Communication” Proc. Nat. Acad. Sci. USA2014111, 18162–18166.

Mirica, K. A.; Azzarelli, J. M.; Weis, J. G.; Schnorr, J. M.; Swager, T. M., “Rapid Prototyping of Carbon-Based Chemiresistive Gas Sensors on Paper” Proc. Nat. Acad. Sci. USA2013110, E3265–E3270.

Mirica, K. A.; Weis, J. G.; Schnorr, J. M.; Esser, B.; Swager, T. M., “Mechanical Drawing of Gas Sensors on Paper” Angew. Chem. Int. Ed., 201251, 10740–10745.

Shapiro, N.D.; Mirica, K. A.; Soh, S.; Phillips, S. T.; Taran, O.; Mace, C. R.; Shevkoplyas, S. S.; Whitesides, G. M. “Measuring Binding of Protein to Gel-Bound Ligands Using Magnetic Levitation” J. Am. Chem. Soc.2012134, 5637–5646.

Mirica, K. A.; Lockett, M.R.; Snyder, P. W.; Shapiro, N. D.; Mack, E. T.; Nam, S.; Whitesides, G. M. “Selective Precipitation and Purification of Monovalent Proteins Using Oligovalent Ligands and Ammonium Sulfate” Bioconjugate Chem.201223, 293–299.

Mirica, K. A.; Ilievski, F.; Ellerbee, A. K.; Shevkoplyas, S. S.; Whitesides, G. M., “Using Magnetic Levitation for Three Dimensional Self-Assembly”, Adv. Mater., 2011, 23, 4134–4140.

Reches, M.; Mirica, K. A.; Dasgupta, R.; Dickey, M. D.; Whitesides, G. M., “Thread as a Matrix for Biomedical Assays” ACS Appl. Mater. Interfaces20102, 1722–1728.

Mirica, K. A.; Shevkoplyas, S. S.; Phillips, S. T.; Gupta, M., and Whitesides, G. M., “Measuring Densities of Solids and Liquids Using Magnetic Levitation: Fundamentals” J. Am. Chem. Soc.2009131, 10049–10058.

Mirica, K. A.; Phillips, S. T.; Shevkoplyas, S. S.; and Whitesides, G. M., “Using Magnetic Levitation to Distinguish Atomic-Level Differences in Chemical Composition of Polymers, and to Monitor Chemical Reactions on Solid Supports” J. Am. Chem. Soc.2008,130, 17678–17680.