News & Events

  • Direct Self-Assembly of Conductive Nanorods of Metal–Organic Frameworks into Chemiresistive Devices on Shrinkable Polymer Films

    Smith, M. K.; Jensen, K. E.; Pivak, P. A.; Mirica, K. A.*, Chem. Mater., 2016, 28, 5264–5268.

    The Mirica Laboratory has developed an exceedingly simple and rapid approach for integrating conductive nanorods of metal organic frameworks (MOFs) into chemiresistive devices on polymeric substrates. This approach involves fabricating thermally miniaturized...

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  • The Micalizio laboratory has established a synthesis pathway to the pentacyclic core of the rare anticancer and antiviral cortistatins by application of their metallacycle-mediated alkoxide-directed annulative cross-coupling reaction. heir route begins with epichlorohydin, establishes the key trans-fused hydrindane in just six steps, with 9 subsequent steps being employed to establish the ABC-tricyclic system.

    To read the article, please click...

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  • Title of project: Stereoselective Synthesis via Metallacycle-Mediated Bond Construction
    Agency: The National Institutes of Health, National Institute of General Medical Sciences
    Amount: $1,393,204
    Duration: four years

    Broad description of research project:  This research project aims to design and develop new stereoselective reactions in organic chemistry.  Effort will be directed...

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  • Please join the Chemistry Department on May 28 as it celebrates the careers of professors David M. Lemal and Russell P. Hughes.

    The Dartmouth Symposium on Fluorine Chemistry will feature plenary talks by internationally recognized fluorine chemists, a poster session, and speaker introductions by professors Lemal and Hughes.

    The symposium will be held at the Hanover Inn and is free and open to the public. Registration is required...

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  • Associate Professor of Chemistry Ivan Aprahamian has won the prestigious Cram Lehn  Pederson (CLP) Prize.  To read the article click here.

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    X. Cheng, G. C. Micalizio “Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R, 10S)-2-oxo-3,4,-dehydroneomajucin, (2S)-hydroxy-3,4-dehydroneomajucin, and (–)-jiadifenin” J. Am. Chem. Soc. 2016, 138, accepted.

    to read the journal article click : Micalizio Publication

  • Presented by the Dartmouth Chemistry Society
    Thursday October 15th
    6:00-6:30pm
    Check-In and Light Refreshments "Under the Globe" Fairchild Towers

    6:30-7:30pm
    101 Fairchild
    Panel Discussion Featuring Chemistry Alumni:

    • Jacob Goldberg
    • John Lane
    • Emma Nairn
    • Katherine Schiavoni
    • John Schneekloth, Jr.

    7:30-9:30pm
    Buffet and Refreshments "Under the Globe" Fairchild Towers

    ...

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  • Alexander Korotkov, Hui Li, Charles W. Chapman, Haoran Xue, John MacMillan, Alan Eastman, and Jimmy Wu
    Angewandte Chemie International Edition, 2015, 54, Early View (DOI: 10.1002/anie.201503934)

    To read the journal article click here.
    To read the news release click here.

     

  • FadR is a regulator of fatty acid metabolism and influences virulence in members of the Vibrio family of enteric bacteria including the bacterium Vibrio cholerae, which is responsible for cholera infection in humans. Recent research by Wei Shi in Jon Kull’s group has shown Vibrio FadR contains an unusual C-terminal 40-amino acid insertion. This insertion allows for the binding of an additional fatty acid ligand that causes a greater conformational change to disrupt DNA binding. Structures...

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  • Visiting third-graders were treated to a delicious treat by the grad students and staff of the Chemistry Dept. The class from Bradford Elementary enjoyed visiting the Ice Core Lab at Thayer, the greenhouse and animal adaptations presentation at LSC, demonstrations by Chemistry & Physics Dept and the liquid Nitrogen ice cream outside of Burke. One third-grader was overheard exclaiming “This is the best field trip ever!”

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